7RIA

Griffithsin variant Y28A/Y68A/Y110A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Griffithsin	polymer	142	14541.8	2	UniProt (P84801) Pfam (PF01419)	Griffithsia sp. (strain Q66D336) (Red alga)	GRFT
2	C, D, E, H, I... (A, B)	alpha-D-mannopyranose	non-polymer		180.2	6	Chemie (MAN)
3	F, G (A)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	K, L (A, B)	water	water		18.0	228	Chemie (HOH)

Sequence modifications

A, B: 2 - 121 (UniProt: P84801)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag
Gly 1	-	expression tag
Ala 28	Tyr 28	engineered mutation
Ala 31	Unk 31	variant
Ala 68	Tyr 68	engineered mutation
Ala 110	Tyr 110	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	29083.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1273.1
All*	Total formula weight	30356.7

*Water molecules are not included.