7RHZ

Heterodimer of Cre recombinase mutants D33A/A36V/R192A and R72E/L115D/R119D in complex with loxP DNA.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Recombinase cre	polymer	343	38493.1	1	UniProt (P06956) Pfam (PF00589) In PDB	Escherichia phage P1 (Bacteriophage P1)
2	B	Recombinase cre	polymer	343	38526.9	1	UniProt (P06956) Pfam (PF00589) In PDB	Escherichia phage P1 (Bacteriophage P1)
3	C	DNA (44-MER)	polymer	44	13491.7	1		Escherichia phage P1
4	D	DNA (44-MER)	polymer	44	13602.7	1		Escherichia phage P1

Sequence modifications

A: 1 - 343 (UniProt: P06956)

PDB	External Database	Details
Ala 33	Asp 33	engineered mutation
Val 36	Ala 36	engineered mutation
Ala 192	Arg 192	engineered mutation

B: 1 - 343 (UniProt: P06956)

PDB	External Database	Details
Glu 72	Arg 72	engineered mutation
Asp 115	Leu 115	engineered mutation
Asp 119	Arg 119	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	104114.4
All*	Total formula weight	104114.4

*Water molecules are not included.