7RHL

Cryo-EM structure of human rod Apo CNGA1/B1 channel with CLZ coiled coil

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, D (C, A, D)	cGMP-gated cation channel alpha-1	polymer	560	64650.4	3	UniProt (P29973) Pfam (PF00520) Pfam (PF00027) Pfam (PF16526)	Homo sapiens (Human)	Cyclic nucleotide-gated cation channel 1,Cyclic nucleotide-gated channel alpha-1,CNG1,Cyclic nucleotide-gated channel,photoreceptor,Rod photoreceptor cGMP-gated channel subunit alpha
2	B (B)	Cyclic nucleotide-gated cation channel beta-1	polymer	810	91039.3	1	UniProt (Q14028) Pfam (PF00027)	Homo sapiens (Human)	Cyclic nucleotide-gated cation channel 4,CNG channel 4,CNG-4,CNG4,Cyclic nucleotide-gated cation channel gamma,Cyclic nucleotide-gated cation channel modulatory subunit,Cyclic nucleotide-gated channel beta-1,CNG channel beta-1,Glutamic acid-rich protein,GARP

Sequence modifications

C, A, D: 144 - 690 (UniProt: P29973)

PDB	External Database	Details
Met 131	-	expression tag
Asp 132	-	expression tag
Tyr 133	-	expression tag
Lys 134	-	expression tag
Asp 135	-	expression tag
Asp 136	-	expression tag
Asp 137	-	expression tag
Asp 138	-	expression tag
Lys 139	-	expression tag
Gly 140	-	expression tag
Gly 141	-	expression tag
Ser 142	-	expression tag
Ala 143	-	expression tag

B: 454 - 1251 (UniProt: Q14028)

PDB	External Database	Details
Met 442	-	expression tag
Asp 443	-	expression tag
Tyr 444	-	expression tag
Lys 445	-	expression tag
Asp 446	-	expression tag
Asp 447	-	expression tag
Asp 448	-	expression tag
Asp 449	-	expression tag
Lys 450	-	expression tag
Gly 451	-	expression tag
Gly 452	-	expression tag
Ser 453	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	284990.6
All*	Total formula weight	284990.6

*Water molecules are not included.