7RGW

Crystal structure of HERC2 DOC domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	E3 ubiquitin-protein ligase HERC2	polymer	174	19588.5	1	UniProt (O95714) Pfam (PF03256)	Homo sapiens (Human)	HECT domain and RCC1-like domain-containing protein 2,HECT-type E3 ubiquitin transferase HERC2
2	B (A)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
3	C (A)	water	water		18.0	183	Chemie (HOH)

Sequence modifications

A: 2759 - 2914 (UniProt: O95714)

PDB	External Database	Details
Met 2741	-	expression tag
His 2742	-	expression tag
His 2743	-	expression tag
His 2744	-	expression tag
His 2745	-	expression tag
His 2746	-	expression tag
His 2747	-	expression tag
Ser 2748	-	expression tag
Ser 2749	-	expression tag
Gly 2750	-	expression tag
Arg 2751	-	expression tag
Glu 2752	-	expression tag
Asn 2753	-	expression tag
Leu 2754	-	expression tag
Tyr 2755	-	expression tag
Phe 2756	-	expression tag
Gln 2757	-	expression tag
Gly 2758	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19588.5
Non-Polymers*	Number of molecules	1
	Total formula weight	106.1
All*	Total formula weight	19694.6

*Water molecules are not included.