7RGQ
HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH GTP, ATP, IMP, NAD+; INTERFACE-CENTERED
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Inosine-5'-monophosphate dehydrogenase 1 | polymer | 546 | 58370.8 | 8 | UniProt (P20839) Pfam (PF00478) Pfam (PF00571) | Homo sapiens (Human) | IMP dehydrogenase 1,IMPD 1,IMPDH 1,IMPDH-I |
| 2 | BA, CA, GA, HA, I... (D, E, F, A, G...) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 16 | Chemie (GTP) | |||
| 3 | DA, IA, J, NA, O... (E, F, A, G, B...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) | |||
| 4 | EA, JA, K, OA, P... (E, F, A, G, B...) | INOSINIC ACID | non-polymer | 348.2 | 8 | Chemie (IMP) | |||
| 5 | AA, FA, KA, L, PA... (D, E, F, A, G...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 509 (UniProt: P20839)
| PDB | External Database | Details |
|---|---|---|
| Thr 510 | - | expression tag |
| Phe 511 | - | expression tag |
| Leu 512 | - | expression tag |
| Pro 513 | - | expression tag |
| Phe 514 | - | expression tag |
| Thr 515 | - | expression tag |
| Lys 516 | - | expression tag |
| Ser 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Cys 519 | - | expression tag |
| Thr 520 | - | expression tag |
| Glu 521 | - | expression tag |
| Asp 522 | - | expression tag |
| Ser 523 | - | expression tag |
| Gly 524 | - | expression tag |
| Gly 525 | - | expression tag |
| Gly 526 | - | expression tag |
| Arg 527 | - | expression tag |
| Gly 528 | - | expression tag |
| Gly 529 | - | expression tag |
| Gly 530 | - | expression tag |
| Gly 531 | - | expression tag |
| Asp 532 | - | expression tag |
| Ala 533 | - | expression tag |
| Pro 534 | - | expression tag |
| Gln 535 | - | expression tag |
| Cys 536 | - | expression tag |
| Pro 537 | - | expression tag |
| Leu 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Gly 540 | - | expression tag |
| Thr 541 | - | expression tag |
| Ala 542 | - | expression tag |
| Ser 543 | - | expression tag |
| Leu 544 | - | expression tag |
| His 545 | - | expression tag |
| Asn 546 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 466966.2 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 20521.4 | |
| All* | Total formula weight | 487487.5 |
