7RGG

Room temperature serial crystal structure of Glutaminase C in complex with inhibitor BPTES

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutaminase kidney isoform, mitochondrial 68 kDa chain	polymer	491	53982.5	4	UniProt (O94925) Pfam (PF17959) Pfam (PF04960)	Homo sapiens (Human)
2	E, F (A, D)	N,N'-[sulfanediylbis(ethane-2,1-diyl-1,3,4-thiadiazole-5,2-diyl)]bis(2-phenylacetamide)	non-polymer		524.7	2	Chemie (04A)
3	G, H (A, D)	water	water		18.0	4	Chemie (HOH)

Sequence modifications

A, B, C, D: 72 - 550 (UniProt: O94925)

PDB	External Database	Details
Met 60	-	expression tag
Arg 61	-	expression tag
Gly 62	-	expression tag
Ser 63	-	expression tag
His 64	-	expression tag
His 65	-	expression tag
His 66	-	expression tag
His 67	-	expression tag
His 68	-	expression tag
His 69	-	expression tag
Gly 70	-	expression tag
Ser 71	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	215930.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1049.4
All*	Total formula weight	216979.4

*Water molecules are not included.