7RGD
HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, OCTAMER-CENTERED
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1 | polymer | 595 | 63407.3 | 8 | UniProt (P20839-5) Pfam (PF00478) Pfam (PF00571) UniProt (by SIFTS) (P20839) | Homo sapiens (Human) | IMP dehydrogenase 1,IMPD 1,IMPDH 1,IMPDH-I |
| 2 | CA, DA, HA, I, IA... (E, F, A, G, B...) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 16 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 3 | EA, JA, K, OA, P... (E, F, A, G, B...) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 8 | Chemie (ATP) | |||
| 4 | AA, FA, KA, L, PA... (D, E, F, A, G...) | INOSINIC ACID | non-polymer | 348.2 | 8 | Chemie (IMP) PubChem (177678963) PubChem (135464200) PubChem (135533971) PubChem (138454308) PubChem (135398640) PubChem (135402036) PubChem (135449337) PubChem (135486133) PubChem (135530792) PubChem (135567013) PubChem (135705234) PubChem (135854804) PubChem (135889742) PubChem (136026456) PubChem (136073920) PubChem (136217866) PubChem (136259539) PubChem (136716177) PubChem (136766861) PubChem (136811071) PubChem (137162990) PubChem (137168789) PubChem (137257909) PubChem (162510533) PubChem (174152734) | |||
| 5 | BA, GA, LA, M, QA... (D, E, F, A, G...) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) |
Sequence modifications
A, B, C, D, E, F, G, H: -48 - 509 (UniProt: P20839-5)
| PDB | External Database | Details |
|---|---|---|
| - | Ser 49 | deletion |
| - | Cys 50 | deletion |
| - | Phe 51 | deletion |
| - | Leu 52 | deletion |
| - | Leu 53 | deletion |
| - | Glu 54 | deletion |
| - | Leu 55 | deletion |
| - | Ser 56 | deletion |
| - | Ser 57 | deletion |
| - | Val 58 | deletion |
| - | Val 59 | deletion |
| - | Leu 60 | deletion |
| - | Leu 61 | deletion |
| - | Ala 62 | deletion |
| - | Gly 63 | deletion |
| - | Val 64 | deletion |
| - | Gly 65 | deletion |
| - | Val 66 | deletion |
| - | Gln 67 | deletion |
| - | Met 68 | deletion |
| - | Asp 69 | deletion |
| - | Arg 70 | deletion |
| - | Leu 71 | deletion |
| - | Arg 72 | deletion |
| - | Arg 73 | deletion |
| - | Ala 74 | deletion |
| Thr 510 | - | expression tag |
| Phe 511 | - | expression tag |
| Leu 512 | - | expression tag |
| Pro 513 | - | expression tag |
| Phe 514 | - | expression tag |
| Thr 515 | - | expression tag |
| Lys 516 | - | expression tag |
| Ser 517 | - | expression tag |
| Gly 518 | - | expression tag |
| Cys 519 | - | expression tag |
| Thr 520 | - | expression tag |
| Glu 521 | - | expression tag |
| Asp 522 | - | expression tag |
| Ser 523 | - | expression tag |
| Gly 524 | - | expression tag |
| Gly 525 | - | expression tag |
| Gly 526 | - | expression tag |
| Arg 527 | - | expression tag |
| Gly 528 | - | expression tag |
| Gly 529 | - | expression tag |
| Gly 530 | - | expression tag |
| Gly 531 | - | expression tag |
| Asp 532 | - | expression tag |
| Ala 533 | - | expression tag |
| Pro 534 | - | expression tag |
| Gln 535 | - | expression tag |
| Cys 536 | - | expression tag |
| Pro 537 | - | expression tag |
| Leu 538 | - | expression tag |
| Leu 539 | - | expression tag |
| Gly 540 | - | expression tag |
| Thr 541 | - | expression tag |
| Ala 542 | - | expression tag |
| Ser 543 | - | expression tag |
| Leu 544 | - | expression tag |
| His 545 | - | expression tag |
| Asn 546 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 507258.6 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 20521.4 | |
| All* | Total formula weight | 527780.0 |
