7RFI
HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, INTERFACE-CENTERED
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1 | polymer | 621 | 66225.7 | 8 | UniProt (P20839-5) Pfam (PF00478) Pfam (PF00571) UniProt (by SIFTS) (Q5H9Q6) In PDB | Homo sapiens (Human) | IMP dehydrogenase 1,IMPD 1,IMPDH 1,IMPDH-I |
2 | F, G, A, H, B... | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 16 | Chemie (GTP) | |||
3 | E, F, G, A, H... | INOSINIC ACID | non-polymer | 348.2 | 8 | Chemie (IMP) | |||
4 | E, F, G, A, H... | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 8 | Chemie (NAD) |
Sequence modifications
A, B, C, D, E, F, G, H: -48 - 509 (UniProt: P20839-5)
PDB | External Database | Details |
---|---|---|
Thr 510 | - | expression tag |
Phe 511 | - | expression tag |
Leu 512 | - | expression tag |
Pro 513 | - | expression tag |
Phe 514 | - | expression tag |
Thr 515 | - | expression tag |
Lys 516 | - | expression tag |
Ser 517 | - | expression tag |
Gly 518 | - | expression tag |
Cys 519 | - | expression tag |
Thr 520 | - | expression tag |
Glu 521 | - | expression tag |
Asp 522 | - | expression tag |
Ser 523 | - | expression tag |
Gly 524 | - | expression tag |
Gly 525 | - | expression tag |
Gly 526 | - | expression tag |
Arg 527 | - | expression tag |
Gly 528 | - | expression tag |
Gly 529 | - | expression tag |
Gly 530 | - | expression tag |
Gly 531 | - | expression tag |
Asp 532 | - | expression tag |
Ala 533 | - | expression tag |
Pro 534 | - | expression tag |
Gln 535 | - | expression tag |
Cys 536 | - | expression tag |
Pro 537 | - | expression tag |
Leu 538 | - | expression tag |
Leu 539 | - | expression tag |
Gly 540 | - | expression tag |
Thr 541 | - | expression tag |
Ala 542 | - | expression tag |
Ser 543 | - | expression tag |
Leu 544 | - | expression tag |
His 545 | - | expression tag |
Asn 546 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 529805.8 | |
Non-Polymers* | Number of molecules | 32 |
Total formula weight | 16463.9 | |
All* | Total formula weight | 546269.7 |