7RDV
TFH TCR bound to MHC Class II IAd presenting aggrecan epitope
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | H-2 class II histocompatibility antigen, A-D alpha chain | polymer | 181 | 20569.0 | 1 | UniProt (P04228) Pfam (PF00993) Pfam (PF07654) In PDB | Mus musculus (Mouse) | |
| 2 | B | H-2 class II histocompatibility antigen, A-D beta chain | polymer | 186 | 21848.3 | 1 | UniProt (P01921) Pfam (PF00969) Pfam (PF07654) In PDB | Mus musculus (Mouse) | |
| 3 | C | TFH TCR alpha chain | polymer | 205 | 23023.4 | 1 | Mus musculus (Mouse) | ||
| 4 | D | TFH TCR beta chain | polymer | 240 | 26829.7 | 1 | Mus musculus (Mouse) | ||
| 5 | H | Aggrecan core peptide | polymer | 12 | 1367.5 | 1 | UniProt (by SIFTS) (P16112) In PDB | Homo sapiens (Human) | |
| 6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 7 | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 1 - 178 (UniProt: P04228)
| PDB | External Database | Details |
|---|---|---|
| Thr 179 | - | expression tag |
| Ser 180 | - | expression tag |
| Gly 181 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 93637.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 94080.3 |
