7RCB

Crystal Structure of a PMS2 VUS

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Mismatch repair endonuclease PMS2	polymer	365	40486.2	2	UniProt (P54278) Pfam (PF13589) Pfam (PF01119) In PDB	Homo sapiens (Human)	DNA mismatch repair protein PMS2,PMS1 protein homolog 2
2		water	water		18.0	401	Chemie (HOH)

Sequence modifications

A, B: 1 - 365 (UniProt: P54278)

PDB	External Database	Details
Ser 335	Asn 335	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80972.4
All*	Total formula weight	80972.4

*Water molecules are not included.