7RB7
Room temperature structure of hAChE in complex with substrate analog 4K-TMA and MMB4 oxime
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Acetylcholinesterase | polymer | 550 | 60288.0 | 2 | UniProt (P22303) Pfam (PF00135) In PDB | Homo sapiens (Human) | AChE |
| 2 | A, B | 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM | non-polymer | 162.3 | 2 | Chemie (NWA) | |||
| 3 | A, B | 1,1'-methylenebis{4-[(E)-(hydroxyimino)methyl]pyridin-1-ium} | non-polymer | 258.3 | 2 | Chemie (3VI) | |||
| 4 | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 547 (UniProt: P22303)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| Leu 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 120576.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 841.1 | |
| All* | Total formula weight | 121417.0 |
