7RAA
Designed StabIL-2 seq15
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Interleukin-2 | polymer | 134 | 15586.1 | 4 | UniProt (P60568) Pfam (PF00715) In PDB | Homo sapiens (Human) | IL-2,T-cell growth factor,TCGF |
| 2 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | water | water | 18.0 | 15 | Chemie (HOH) |
Sequence modifications
A, B, C, D: -4 - 128 (UniProt: P60568)
| PDB | External Database | Details |
|---|---|---|
| Met -5 | - | initiating methionine |
| Met 22 | Gly 47 | engineered mutation |
| Leu 23 | Ile 48 | engineered mutation |
| Asp 27 | Lys 52 | engineered mutation |
| Ala 64 | Val 89 | engineered mutation |
| Gln 67 | Leu 92 | engineered mutation |
| Asp 76 | Arg 101 | engineered mutation |
| Ile 110 | Val 135 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62344.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 62392.9 |
