7R8B
The structure of human ABCG5/ABCG8 supplemented with cholesterol
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-binding cassette sub-family G member 5 | polymer | 666 | 74437.4 | 1 | UniProt (Q9H222) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (Human) | Sterolin-1 |
| 2 | B (B) | ATP-binding cassette sub-family G member 8 | polymer | 715 | 80365.8 | 1 | UniProt (Q9H221) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (Human) | Sterolin-2 |
| 3 | C (C) | 2C7 Fab heavy chain | polymer | 245 | 26379.7 | 1 | Mus musculus | ||
| 4 | D (D) | 2C7 Fab light chain | polymer | 234 | 25605.6 | 1 | Mus musculus | ||
| 5 | E, F (A, B) | CHOLESTEROL | non-polymer | 386.7 | 2 | Chemie (CLR) |
Sequence modifications
A: 1 - 651 (UniProt: Q9H222)
B: 1 - 673 (UniProt: Q9H221)
| PDB | External Database | Details |
|---|---|---|
| Gly 652 | - | expression tag |
| Ser 653 | - | expression tag |
| His 654 | - | expression tag |
| His 655 | - | expression tag |
| His 656 | - | expression tag |
| His 657 | - | expression tag |
| His 658 | - | expression tag |
| His 659 | - | expression tag |
| Gly 660 | - | expression tag |
| His 661 | - | expression tag |
| His 662 | - | expression tag |
| His 663 | - | expression tag |
| His 664 | - | expression tag |
| His 665 | - | expression tag |
| His 666 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 674 | - | expression tag |
| Ser 675 | - | expression tag |
| Asn 676 | - | expression tag |
| Ser 677 | - | expression tag |
| Leu 678 | - | expression tag |
| Glu 679 | - | expression tag |
| Val 680 | - | expression tag |
| Leu 681 | - | expression tag |
| Phe 682 | - | expression tag |
| Gln 683 | - | expression tag |
| Gly 684 | - | expression tag |
| Pro 685 | - | expression tag |
| Asn 686 | - | expression tag |
| Val 687 | - | expression tag |
| Asp 688 | - | expression tag |
| Ser 689 | - | expression tag |
| Lys 690 | - | expression tag |
| Arg 691 | - | expression tag |
| Arg 692 | - | expression tag |
| Trp 693 | - | expression tag |
| Lys 694 | - | expression tag |
| Lys 695 | - | expression tag |
| Asn 696 | - | expression tag |
| Phe 697 | - | expression tag |
| Ile 698 | - | expression tag |
| Ala 699 | - | expression tag |
| Val 700 | - | expression tag |
| Ser 701 | - | expression tag |
| Ala 702 | - | expression tag |
| Ala 703 | - | expression tag |
| Asn 704 | - | expression tag |
| Arg 705 | - | expression tag |
| Phe 706 | - | expression tag |
| Lys 707 | - | expression tag |
| Lys 708 | - | expression tag |
| Ile 709 | - | expression tag |
| Ser 710 | - | expression tag |
| Ser 711 | - | expression tag |
| Ser 712 | - | expression tag |
| Gly 713 | - | expression tag |
| Ala 714 | - | expression tag |
| Leu 715 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 206788.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 773.3 | |
| All* | Total formula weight | 207561.8 |
