7R8A
The structure of human ABCG5/ABCG8 purified from mammalian cells
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ATP-binding cassette sub-family G member 5 | polymer | 666 | 74437.4 | 1 | UniProt (Q9H222) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (Human) | Sterolin-1 |
| 2 | B (B) | ATP-binding cassette sub-family G member 8 | polymer | 715 | 80365.8 | 1 | UniProt (Q9H221) Pfam (PF00005) Pfam (PF19055) Pfam (PF01061) | Homo sapiens (Human) | Sterolin-2 |
| 3 | C (C) | 2C7 Fab heavy chain | polymer | 245 | 26379.7 | 1 | Mus musculus | ||
| 4 | D (D) | 2C7 Fab light chain | polymer | 234 | 25605.6 | 1 | Mus musculus | ||
| 5 | E (A) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (304) PubChem (176980071) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (18640088) PubChem (1715243) PubChem (1715244) PubChem (45044259) PubChem (23423981) PubChem (49853509) PubChem (50990013) PubChem (52934537) PubChem (56621683) PubChem (191463) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (368063) PubChem (369319) PubChem (44654663) PubChem (59450329) PubChem (59628412) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (46937002) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (638019) PubChem (59274407) PubChem (1549081) PubChem (1553803) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (89951918) PubChem (90224410) PubChem (5997) PubChem (5283629) PubChem (5284644) PubChem (1551269) PubChem (90070115) PubChem (91298236) PubChem (5315842) PubChem (117965027) PubChem (6432564) PubChem (6710666) PubChem (124146240) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (6419195) PubChem (10861996) PubChem (132837164) PubChem (101624109) PubChem (6994560) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (124225449) PubChem (138967089) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (139566851) PubChem (124429284) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (15939944) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (171828367) PubChem (173516975) PubChem (130459183) PubChem (131992107) PubChem (139568882) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) |
Sequence modifications
A: 1 - 651 (UniProt: Q9H222)
B: 1 - 673 (UniProt: Q9H221)
| PDB | External Database | Details |
|---|---|---|
| Gly 652 | - | expression tag |
| Ser 653 | - | expression tag |
| His 654 | - | expression tag |
| His 655 | - | expression tag |
| His 656 | - | expression tag |
| His 657 | - | expression tag |
| His 658 | - | expression tag |
| His 659 | - | expression tag |
| Gly 660 | - | expression tag |
| His 661 | - | expression tag |
| His 662 | - | expression tag |
| His 663 | - | expression tag |
| His 664 | - | expression tag |
| His 665 | - | expression tag |
| His 666 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 674 | - | expression tag |
| Ser 675 | - | expression tag |
| Asn 676 | - | expression tag |
| Ser 677 | - | expression tag |
| Leu 678 | - | expression tag |
| Glu 679 | - | expression tag |
| Val 680 | - | expression tag |
| Leu 681 | - | expression tag |
| Phe 682 | - | expression tag |
| Gln 683 | - | expression tag |
| Gly 684 | - | expression tag |
| Pro 685 | - | expression tag |
| Asn 686 | - | expression tag |
| Val 687 | - | expression tag |
| Asp 688 | - | expression tag |
| Ser 689 | - | expression tag |
| Lys 690 | - | expression tag |
| Arg 691 | - | expression tag |
| Arg 692 | - | expression tag |
| Trp 693 | - | expression tag |
| Lys 694 | - | expression tag |
| Lys 695 | - | expression tag |
| Asn 696 | - | expression tag |
| Phe 697 | - | expression tag |
| Ile 698 | - | expression tag |
| Ala 699 | - | expression tag |
| Val 700 | - | expression tag |
| Ser 701 | - | expression tag |
| Ala 702 | - | expression tag |
| Ala 703 | - | expression tag |
| Asn 704 | - | expression tag |
| Arg 705 | - | expression tag |
| Phe 706 | - | expression tag |
| Lys 707 | - | expression tag |
| Lys 708 | - | expression tag |
| Ile 709 | - | expression tag |
| Ser 710 | - | expression tag |
| Ser 711 | - | expression tag |
| Ser 712 | - | expression tag |
| Gly 713 | - | expression tag |
| Ala 714 | - | expression tag |
| Leu 715 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 206788.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 386.7 | |
| All* | Total formula weight | 207175.1 |
