7R75
Structure of human SHP2 in complex with compound 16
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Tyrosine-protein phosphatase non-receptor type 11 | polymer | 536 | 61491.4 | 1 | UniProt (Q06124) Pfam (PF00017) Pfam (PF00102) In PDB | Homo sapiens (Human) | Protein-tyrosine phosphatase 1D,PTP-1D,Protein-tyrosine phosphatase 2C,PTP-2C,SH-PTP2,Shp2,SH-PTP3 |
2 | A | 6-(4-amino-4-methylpiperidin-1-yl)-3-(3-chlorophenyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one | non-polymer | 358.8 | 1 | Chemie (33I) |
Sequence modifications
A: 1 - 530 (UniProt: Q06124)
PDB | External Database | Details |
---|---|---|
Gly -5 | - | expression tag |
Ala -4 | - | expression tag |
Met -3 | - | expression tag |
Ala -2 | - | expression tag |
Asp -1 | - | expression tag |
Ile 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 61491.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 358.8 | |
All* | Total formula weight | 61850.2 |