7R5M

Core-binding domain of fungal E3-binding domain bound to the pyruvate dehydrogenase E2 core

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, G, H, K...	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial	polymer	235	25195.0	6	UniProt (P20285) Pfam (PF00198) In PDB	Neurospora crassa	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex,MRP3,Pyruvate dehydrogenase complex component E2,PDC-E2,PDCE2
2	F, J, M	Pyruvate dehydrogenase X component	polymer	189	20476.2	3	UniProt (Q7RWS2) In PDB	Neurospora crassa

Sequence modifications

A, B, G, H, K, L: 225 - 458 (UniProt: P20285)

PDB	External Database	Details
Met 224	-	initiating methionine

F, J, M: 261 - 426 (UniProt: Q7RWS2)

PDB	External Database	Details
His 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
Ser 244	-	expression tag
Gln 245	-	expression tag
Asp 246	-	expression tag
Pro 247	-	expression tag
Asn 248	-	expression tag
Ser 249	-	expression tag
Ser 250	-	expression tag
Pro 251	-	expression tag
Ser 252	-	expression tag
Ser 253	-	expression tag
Glu 254	-	expression tag
Asn 255	-	expression tag
Leu 256	-	expression tag
Tyr 257	-	expression tag
Phe 258	-	expression tag
Gln 259	-	expression tag
Ser 260	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	9
	Total formula weight	212598.4
All*	Total formula weight	212598.4

*Water molecules are not included.