7R59
PARP2 catalytic domain in complex with OUL245
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Poly [ADP-ribose] polymerase 2 | polymer | 351 | 39896.9 | 1 | UniProt (Q9UGN5) Pfam (PF02877) Pfam (PF00644) In PDB | Homo sapiens (human) | PARP-2,hPARP-2,ADP-ribosyltransferase diphtheria toxin-like 2,ARTD2,DNA ADP-ribosyltransferase PARP2,NAD(+) ADP-ribosyltransferase 2,ADPRT-2,Poly[ADP-ribose] synthase 2,pADPRT-2,Protein poly-ADP-ribosyltransferase PARP2 |
| 2 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | A | [1,2,4]triazolo[3,4-b][1,3]benzothiazol-6-ol | non-polymer | 191.2 | 1 | Chemie (I5F) | |||
| 4 | water | water | 18.0 | 199 | Chemie (HOH) |
Sequence modifications
A: 235 - 583 (UniProt: Q9UGN5)
| PDB | External Database | Details |
|---|---|---|
| Ser 233 | - | expression tag |
| Met 234 | - | expression tag |
| His 447 | Pro 447 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39896.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 283.3 | |
| All* | Total formula weight | 40180.2 |
