7R2M

SYNJ2BP complex with a synthetic Vangl2 peptide (9mer).

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (D, A)	Synaptojanin-2-binding protein,Annexin	polymer	422	47775.0	2	UniProt (P57105) UniProt (A0A4W2GEM6) Pfam (PF00595)	Homo sapiens (human)	Mitochondrial outer membrane protein 25
2	C, D (B, E)	Vangl2 peptide	polymer	24	2486.7	2	UniProt (by SIFTS) (Q9ULK5)	Homo sapiens
3	E, F, G, H, L... (D, A)	CALCIUM ION	non-polymer		40.1	9	Chemie (CA)
4	I, J, P, Q (D, A)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
5	K (D)	2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		354.4	1	Chemie (PE4)
6	S, T (D, A)	water	water		18.0	80	Chemie (HOH)

Sequence modifications

D, A: 6 - 103 (UniProt: P57105)

PDB	External Database	Details
Gln 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
His 4	-	expression tag
Met 5	-	expression tag
Gly 104	-	linker

D, A: 105 - 422 (UniProt: A0A4W2GEM6)

PDB	External Database	Details
Ile 243	Val 209	conflict
Pro 306	Cys 272	conflict
Asp 313	Glu 279	conflict
Arg 328	Lys 294	conflict
Arg 392	Lys 358	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	100523.4
Non-Polymers*	Number of molecules	14
	Total formula weight	1083.5
All*	Total formula weight	101606.9

*Water molecules are not included.