7R2I
Human Cyclophilin D in complex with fragment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 165 | 17783.3 | 1 | UniProt (P30405) Pfam (PF00160) In PDB | Homo sapiens (human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F |
| 2 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | A | ethyl 7-methyl-2-oxidanylidene-1,3-dihydropyrazolo[1,5-a]pyrimidine-6-carboxylate | non-polymer | 221.2 | 1 | Chemie (UPZ) | |||
| 4 | A | PENTAETHYLENE GLYCOL | non-polymer | 238.3 | 1 | Chemie (1PE) | |||
| 5 | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
A: 2 - 165 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ile 133 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17783.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 537.6 | |
| All* | Total formula weight | 18320.9 |
