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7R23

Crystal structure of human Arc CTD in complex with two anti-Arc nanobodies

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ARCpolymer18121743.41UniProt (A0A3L7I2Q1)
Pfam (PF21395)
Pfam (PF18162)
UniProt (by SIFTS) (Q7LC44)
Homo sapiens (human)
2B
(B)
Chains: Bpolymer12814078.61Vicugna pacos
3C
(C)
Chains: Cpolymer12013127.61Vicugna pacos
Sequence modifications
A: 206 - 361 (UniProt: A0A3L7I2Q1)
PDBExternal DatabaseDetails
Met 181-initiating methionine
His 182-expression tag
His 183-expression tag
His 184-expression tag
His 185-expression tag
His 186-expression tag
His 187-expression tag
Leu 188-expression tag
Glu 189-expression tag
Ser 190-expression tag
Thr 191-expression tag
Ser 192-expression tag
Leu 193-expression tag
Tyr 194-expression tag
Lys 195-expression tag
Lys 196-expression tag
Ala 197-expression tag
Gly 198-expression tag
Ser 199-expression tag
Glu 200-expression tag
Asn 201-expression tag
Leu 202-expression tag
Tyr 203-expression tag
Phe 204-expression tag
Gln 205-expression tag
Asp 317Glu 454conflict
Asp 358Gly 495conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight48949.6
All*Total formula weight48949.6
*Water molecules are not included.

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PDB entries from 2025-12-17

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