7QZB
BAZ2A bromodomain in complex with acetylpyrrole derivative compound 98
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bromodomain adjacent to zinc finger domain protein 2A | polymer | 105 | 12363.9 | 1 | UniProt (Q9UIF9) Pfam (PF00439) | Homo sapiens (human) | Transcription termination factor I-interacting protein 5,Tip5,hWALp3 |
| 2 | B (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | C (A) | 3-methyl-1-[2-[4-[(4-methyl-1~{H}-pyrazol-3-yl)methyl]piperazin-1-yl]-1,3-thiazol-4-yl]-2,5,6,7-tetrahydroisoindol-4-one | non-polymer | 410.5 | 1 | Chemie (GI0) | |||
| 4 | D (A) | water | water | 18.0 | 61 | Chemie (HOH) |
Sequence modifications
A: 1796 - 1898 (UniProt: Q9UIF9)
| PDB | External Database | Details |
|---|---|---|
| Ser 1794 | - | expression tag |
| Met 1795 | - | expression tag |
| His 1845 | Glu 1845 | engineered mutation |
| Ser 1848 | Leu 1848 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12363.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 472.6 | |
| All* | Total formula weight | 12836.5 |
