7QZ0
BAZ2A bromodomain in complex with acetylpyrrole derivative compound 83
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Bromodomain adjacent to zinc finger domain protein 2A | polymer | 105 | 12363.9 | 1 | UniProt (Q9UIF9) Pfam (PF00439) In PDB | Homo sapiens (human) | Transcription termination factor I-interacting protein 5,Tip5,hWALp3 |
2 | A | 2-[4-(3-methyl-4-oxidanylidene-2,5,6,7-tetrahydroisoindol-1-yl)-1,3-thiazol-2-yl]guanidine | non-polymer | 289.4 | 2 | Chemie (GQX) | |||
3 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
4 | water | water | 18.0 | 62 | Chemie (HOH) |
Sequence modifications
A: 1796 - 1898 (UniProt: Q9UIF9)
PDB | External Database | Details |
---|---|---|
Ser 1794 | - | expression tag |
Met 1795 | - | expression tag |
His 1845 | Glu 1845 | engineered mutation |
Ser 1848 | Leu 1848 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 12363.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 603.0 | |
All* | Total formula weight | 12966.9 |