7QYU
BAZ2A bromodomain in complex with acetylpyrrole derivative compound 88
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain adjacent to zinc finger domain protein 2A | polymer | 105 | 12363.9 | 1 | UniProt (Q9UIF9) Pfam (PF00439) In PDB | Homo sapiens (human) | Transcription termination factor I-interacting protein 5,Tip5,hWALp3 |
| 2 | A | 2-[4-[[4-[4-(4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrol-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]methyl]-1,2,3-triazol-1-yl]ethanamide | non-polymer | 456.6 | 1 | Chemie (GJC) | |||
| 3 | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 1796 - 1898 (UniProt: Q9UIF9)
| PDB | External Database | Details |
|---|---|---|
| Ser 1794 | - | expression tag |
| Met 1795 | - | expression tag |
| His 1845 | Glu 1845 | engineered mutation |
| Ser 1848 | Leu 1848 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12363.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 456.6 | |
| All* | Total formula weight | 12820.4 |
