7QYH
Structure of plasmepsin II in complex with 2-aminoquinazolin-4(3H)-one based open-flap inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Plasmepsin II | polymer | 329 | 36909.6 | 4 | UniProt (Q8I6V3) Pfam (PF00026) | Plasmodium falciparum 3D7 | Plasmepsin 2 |
| 2 | E (A) | 2-azanyl-3-[[(2~{R})-oxolan-2-yl]methyl]-7-(5-phenylpentyl)quinazolin-4-one | non-polymer | 391.5 | 1 | Chemie (I0J) |
Sequence modifications
A, B, C, D: 1 - 329 (UniProt: Q8I6V3)
| PDB | External Database | Details |
|---|---|---|
| Ser 205 | Met 329 | conflict |
| His 318 | Gln 442 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 147638.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 391.5 | |
| All* | Total formula weight | 148030.0 |
