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7QXU

Proteasome-ZFAND5 Complex Z+C state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(U)
26S proteasome non-ATPase regulatory subunit 1polymer953105958.21UniProt (Q99460)
Pfam (PF21505)
Pfam (PF01851)
Pfam (PF13646)
Pfam (PF18004)
Homo sapiens (human)26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112
2B
(V)
26S proteasome non-ATPase regulatory subunit 3polymer53360935.31UniProt (O43242)
Pfam (PF01399)
Pfam (PF08375)
Homo sapiens (human)26S proteasome regulatory subunit RPN3,26S proteasome regulatory subunit S3,Proteasome subunit p58
3C
(W)
26S proteasome non-ATPase regulatory subunit 12polymer45652979.41UniProt (O00232)
Pfam (PF22241)
Pfam (PF01399)
Pfam (PF18098)
Homo sapiens (human)26S proteasome regulatory subunit RPN5,26S proteasome regulatory subunit p55
4D
(X)
26S proteasome non-ATPase regulatory subunit 11polymer42247526.71UniProt (O00231)
Pfam (PF18055)
Pfam (PF01399)
Pfam (PF18503)
Homo sapiens (human)26S proteasome regulatory subunit RPN6,26S proteasome regulatory subunit S9,26S proteasome regulatory subunit p44.5
5E
(Y)
26S proteasome non-ATPase regulatory subunit 6polymer38945592.31UniProt (Q15008)
Pfam (PF10602)
Pfam (PF01399)
Pfam (PF21154)
Homo sapiens (human)26S proteasome regulatory subunit RPN7,26S proteasome regulatory subunit S10,Breast cancer-associated protein SGA-113M,Phosphonoformate immuno-associated protein 4,Proteasome regulatory particle subunit p44S10,p42A
6F
(Z)
26S proteasome non-ATPase regulatory subunit 7polymer32437086.41UniProt (P51665)
Pfam (PF01398)
Pfam (PF13012)
Homo sapiens (human)26S proteasome regulatory subunit RPN8,26S proteasome regulatory subunit S12,Mov34 protein homolog,Proteasome subunit p40
7G
(a)
26S proteasome non-ATPase regulatory subunit 13polymer37642995.41UniProt (Q9UNM6)
Pfam (PF22037)
Pfam (PF01399)
Homo sapiens (human)26S proteasome regulatory subunit RPN9,26S proteasome regulatory subunit S11,26S proteasome regulatory subunit p40.5
8H
(b)
26S proteasome non-ATPase regulatory subunit 4polymer37740781.61UniProt (P55036)
Pfam (PF13519)
Pfam (PF02809)
Homo sapiens (human)26S proteasome regulatory subunit RPN10,26S proteasome regulatory subunit S5A,Antisecretory factor 1,ASF,Multiubiquitin chain-binding protein
9I
(c)
26S proteasome non-ATPase regulatory subunit 14polymer30934488.81UniProt (O00487)
Pfam (PF01398)
Homo sapiens (human)26S proteasome regulatory subunit RPN11,26S proteasome-associated PAD1 homolog 1
10J
(d)
26S proteasome non-ATPase regulatory subunit 8polymer34939536.71UniProt (P48556)
Pfam (PF10075)
Homo sapiens (human)26S proteasome regulatory subunit RPN12,26S proteasome regulatory subunit S14,p31
11K
(e)
26S proteasome complex subunit SEM1polymer708284.61UniProt (P60896)
Pfam (PF05160)
Homo sapiens (human)26S proteasome complex subunit DSS1,Deleted in split hand/split foot protein 1,Split hand/foot deleted protein 1,Split hand/foot malformation type 1 protein
12L
(f)
26S proteasome non-ATPase regulatory subunit 2polymer908100313.61UniProt (Q13200)
Pfam (PF17781)
Pfam (PF01851)
Pfam (PF18051)
Homo sapiens (human)26S proteasome regulatory subunit RPN1,26S proteasome regulatory subunit S2,26S proteasome subunit p97,Protein 55.11,Tumor necrosis factor type 1 receptor-associated protein 2
13M
(A)
26S protease regulatory subunit 7polymer43348700.81UniProt (P35998)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
Homo sapiens (human)26S proteasome AAA-ATPase subunit RPT1,Proteasome 26S subunit ATPase 2,Protein MSS1
14N
(B)
26S proteasome regulatory subunit 4polymer42948043.21UniProt (P62191)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Homo sapiens (human)P26s4,26S proteasome AAA-ATPase subunit RPT2,Proteasome 26S subunit ATPase 1
15O
(C)
26S proteasome regulatory subunit 8polymer38943719.71Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
UniProt (by SIFTS) (P62195)
Homo sapiens (human)
16P
(D)
26S protease regulatory subunit 6Bpolymer41847426.11UniProt (P43686)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Homo sapiens (human)26S proteasome AAA-ATPase subunit RPT3,MB67-interacting protein,MIP224,Proteasome 26S subunit ATPase 4,Tat-binding protein 7,TBP-7
17Q
(E)
26S proteasome regulatory subunit 10Bpolymer40345867.01UniProt (A0A087X2I1)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
UniProt (by SIFTS) (P62333)
Homo sapiens (human)
18R
(F)
26S protease regulatory subunit 6Apolymer43949266.51UniProt (P17980)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
Homo sapiens (human)26S proteasome AAA-ATPase subunit RPT5,Proteasome 26S subunit ATPase 3,Proteasome subunit P50,Tat-binding protein 1,TBP-1
19GA, S
(G, g)
Proteasome subunit alpha type-6polymer24527301.32UniProt (P60900)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)27 kDa prosomal protein,PROS-27,p27K,Macropain iota chain,Multicatalytic endopeptidase complex iota chain,Proteasome iota chain
20HA, T
(H, h)
Proteasome subunit alpha type-2polymer23325796.32UniProt (P25787)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3
21IA, U
(I, i)
Proteasome subunit alpha type-4polymer26029394.62UniProt (P25789)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L
22JA, V
(J, j)
Proteasome subunit alpha type-7polymer24727798.72UniProt (O14818)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Proteasome subunit RC6-1,Proteasome subunit XAPC7
23KA, W
(K, k)
Proteasome subunit alpha type-5polymer24026304.82UniProt (P28066)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain zeta chain,Multicatalytic endopeptidase complex zeta chain,Proteasome zeta chain
24LA, X
(L, l)
Isoform Long of Proteasome subunit alpha type-1polymer26830150.32UniProt (P25786)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)30 kDa prosomal protein,PROS-30,Macropain subunit C2,Multicatalytic endopeptidase complex subunit C2,Proteasome component C2,Proteasome nu chain
25MA, Y
(M, m)
Proteasome subunit alpha type-3polymer25428338.12UniProt (P25788)
Pfam (PF10584)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C8,Multicatalytic endopeptidase complex subunit C8,Proteasome component C8
26NA, Z
(N, n)
Proteasome subunit beta type-6polymer23825246.52UniProt (P28072)
Pfam (PF00227)
Homo sapiens (human)Macropain delta chain,Multicatalytic endopeptidase complex delta chain,Proteasome delta chain,Proteasome subunit Y
27AA, OA
(O, o)
Proteasome subunit beta type-7polymer27629869.22UniProt (Q99436)
Pfam (PF00227)
Pfam (PF12465)
Homo sapiens (human)Macropain chain Z,Multicatalytic endopeptidase complex chain Z,Proteasome subunit Z
28BA, PA
(P, p)
Proteasome subunit beta type-3polymer20422841.72UniProt (P49720)
Pfam (PF00227)
Homo sapiens (human)Proteasome chain 13,Proteasome component C10-II,Proteasome theta chain
29CA, QA
(Q, q)
Proteasome subunit beta type-2polymer20122864.32UniProt (P49721)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C7-I,Multicatalytic endopeptidase complex subunit C7-I,Proteasome component C7-I
30DA, RA
(R, r)
Proteasome subunit beta type-5polymer26228379.12UniProt (P28074)
Pfam (PF00227)
Homo sapiens (human)Macropain epsilon chain,Multicatalytic endopeptidase complex epsilon chain,Proteasome chain 6,Proteasome epsilon chain,Proteasome subunit MB1,Proteasome subunit X
31EA, SA
(S, s)
Proteasome subunit beta type-1polymer24026391.22UniProt (P20618)
Pfam (PF00227)
Homo sapiens (human)Macropain subunit C5,Multicatalytic endopeptidase complex subunit C5,Proteasome component C5,Proteasome gamma chain
32FA, TA
(T, t)
Proteasome subunit beta type-4polymer26329100.02UniProt (P28070)
Pfam (PF00227)
Homo sapiens (human)26 kDa prosomal protein,HsBPROS26,PROS-26,Macropain beta chain,Multicatalytic endopeptidase complex beta chain,Proteasome beta chain,Proteasome chain 3,HsN3
33UA
(c)
ZINC IONnon-polymer65.41Chemie (ZN)
34AB, CB, VA, XA
(D, E, A, B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.24Chemie (ATP)
35BB, DB, FB, WA, YA
(D, E, F, A, B)
MAGNESIUM IONnon-polymer24.35Chemie (MG)
36EB, ZA
(F, C)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.22Chemie (ADP)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains46
Total formula weight1659054.2
Non-Polymers*Number of molecules12
Total formula weight3070.1
All*Total formula weight1662124.2
*Water molecules are not included.

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PDB entries from 2024-11-06

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