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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7QWQ

Ternary complex of ribosome nascent chain with SRP and NAC

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(1)		SRP RNA 7SLpolymer16754095.21GenBank (23924)Homo sapiens (human)
2B
(q)		Signal recognition particle 19 kDa proteinpolymer14416183.71UniProt (P09132)
Pfam (PF01922)		Homo sapiens (human)SRP19
3C
(s)		Nascent chain preprolactinpolymer1129549.81Homo sapiens (Human)
4D
(u)		Isoform 2 of Transcription factor BTF3polymer16217724.01UniProt (P20290)
Pfam (PF01849)		Homo sapiens (human)Nascent polypeptide-associated complex subunit beta,NAC-beta,RNA polymerase B transcription factor 3
5E
(v)		Signal recognition particle subunit SRP68polymer62770831.61UniProt (Q9UHB9)
Pfam (PF16969)		Homo sapiens (human)SRP68,Signal recognition particle 68 kDa protein
6F
(x)		Signal recognition particle 54 kDa proteinpolymer50455847.71UniProt (P61011)
Pfam (PF02881)
Pfam (PF00448)
Pfam (PF02978)		Homo sapiens (human)SRP54
7G
(A)		L8polymer24426570.11UniProt (G1TT27)
Pfam (PF00181)
Pfam (PF03947)		Oryctolagus cuniculus (rabbit)
8H
(b)		60S ribosomal protein L29polymer22324608.21UniProt (G1TN82)
Pfam (PF01779)
UniProt (by SIFTS) (G1SGR6)		Oryctolagus cuniculus (rabbit)
9I
(5)		28S rRNApolymer47541539032.01Oryctolagus cuniculus (rabbit)
10J
(B)		uL3polymer40346108.01UniProt (G1TL06)
Pfam (PF00297)		Homo sapiens (human)
11K
(c)		60S ribosomal protein L30polymer11512821.11UniProt (G1TDL2)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
12L
(C)		60S ribosomal protein L4polymer41346388.91UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)		Oryctolagus cuniculus (rabbit)
13M
(d)		Ribosomal protein L31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)		Oryctolagus cuniculus (rabbit)eL31
14N
(D)		Ribosomal_L18_c domain-containing proteinpolymer29734481.81UniProt (G1SYJ6)
UniProt (by SIFTS) (P19949)		Oryctolagus cuniculus (rabbit)
15O
(e)		Ribosomal protein L32polymer15718350.01UniProt (G1TUN8)
Pfam (PF01655)		Oryctolagus cuniculus (rabbit)eL32
16P
(E)		60S ribosomal protein L6polymer29133055.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)		Oryctolagus cuniculus (rabbit)
17Q
(f)		60S ribosomal protein L35apolymer11012580.81UniProt (G1SF08)
Pfam (PF01247)		Oryctolagus cuniculus (rabbit)eL33
18R
(F)		uL30polymer22526662.81UniProt (G1SV32)
Pfam (PF08079)
Pfam (PF00327)		Oryctolagus cuniculus (rabbit)
19S
(g)		60S ribosomal protein L34polymer12914557.51UniProt (G1U945)
Pfam (PF01199)
UniProt (by SIFTS) (G1TXG5)		Oryctolagus cuniculus (rabbit)
20T
(G)		60S ribosomal protein L7apolymer31936267.61UniProt (G1STW0)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
21U
(h)		60S ribosomal protein L35polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)		Oryctolagus cuniculus (rabbit)uL29
22V
(H)		60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)		Oryctolagus cuniculus (rabbit)
23W
(i)		60S ribosomal protein L36polymer10211888.41UniProt (G1TTQ5)
Pfam (PF01158)		Oryctolagus cuniculus (rabbit)
24X
(I)		60S ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)		Oryctolagus cuniculus (rabbit)Ribosomal protein L10 (Predicted)
25Y
(j)		Ribosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)		Oryctolagus cuniculus (rabbit)
26Z
(J)		Ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)		Oryctolagus cuniculus (rabbit)
27AA
(k)		60S ribosomal protein L38polymer698107.81UniProt (B5FYZ2)
Pfam (PF01781)		Oryctolagus cuniculus (rabbit)
28BA
(L)		60S ribosomal protein L13polymer21024216.51UniProt (G1TPV0)Oryctolagus cuniculus (rabbit)
29CA
(l)		Ribosomal protein L39polymer516426.81UniProt (G1SYU7)
Pfam (PF00832)		Oryctolagus cuniculus (rabbit)eL39
30DA
(M)		60S ribosomal protein L14polymer21823810.41UniProt (U3KNW6)
Pfam (PF01929)
UniProt (by SIFTS) (G1SZ12)		Oryctolagus cuniculus (rabbit)
31EA
(m)		Ubiquitin A-52 residue ribosomal protein fusion product 1polymer12814758.41UniProt (A0A2U3YV30)
Pfam (PF00240)
Pfam (PF01020)		Oryctolagus cuniculus (rabbit)Ubiquitin-60S ribosomal protein L40
32FA
(N)		Ribosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)		Oryctolagus cuniculus (rabbit)
33GA
(n)		60s ribosomal protein l41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)		Oryctolagus cuniculus (rabbit)eL41
34HA
(O)		60S ribosomal protein L13apolymer50056501.61UniProt (A0A287B929)
Pfam (PF02947)		Oryctolagus cuniculus (rabbit)
35IA
(o)		eL42polymer14116130.21UniProt (A0A5F9D391)
Pfam (PF00935)		Oryctolagus cuniculus (rabbit)
36JA
(P)		60S ribosomal protein L17polymer15317758.71Oryctolagus cuniculus (rabbit)
37KA
(p)		eL43polymer9210299.41UniProt (G1SY53)
Pfam (PF01780)		Oryctolagus cuniculus (rabbit)
38LA
(Q)		eL18polymer18721457.41Oryctolagus cuniculus (rabbit)
39MA
(r)		60S ribosomal protein L28polymer13715783.61UniProt (G1U7L1)
Pfam (PF01778)		Oryctolagus cuniculus (rabbit)eL28
40NA
(R)		60S ribosomal protein L19polymer19623535.31UniProt (Q3T0W9)
Pfam (PF01280)		Oryctolagus cuniculus (rabbit)eL19
41OA
(S)		60S ribosomal protein L18apolymer17520696.41Oryctolagus cuniculus (rabbit)
42PA
(T)		60S ribosomal protein L21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)		Oryctolagus cuniculus (rabbit)eL21
43QA
(U)		Ribosomal protein L22polymer10211836.61Oryctolagus cuniculus (rabbit)
44RA
(V)		Ribosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)		Oryctolagus cuniculus (rabbit)
45SA
(W)		Ribosomal protein L24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)		Oryctolagus cuniculus (rabbit)eL24
46TA
(X)		Ribosomal_L23eN domain-containing proteinpolymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)		Oryctolagus cuniculus (rabbit)uL23
47UA
(7)		5S ribosomal RNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus (rabbit)
48VA
(Y)		Ribosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)		Oryctolagus cuniculus (rabbit)
49WA
(8)		5.8S ribosomal RNApolymer15650143.61GenBank (4CXE_3)Oryctolagus cuniculus (rabbit)
50XA
(Z)		60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)		Oryctolagus cuniculus (rabbit)
51YA
(a)		60S ribosomal protein L27apolymer14816620.61UniProt (G1SNY0)
Pfam (PF00828)		Oryctolagus cuniculus (rabbit)
52ZA
(t)		Nascent polypeptide-associated complex subunit alphapolymer21523406.81UniProt (Q13765)
Pfam (PF01849)
Pfam (PF19026)		Homo sapiens (human)NAC-alpha,Alpha-NAC
53AB, AC, AD, AE, BB...
(5, B)		MAGNESIUM IONnon-polymer24.397Chemie (MG)
54TE, UE, VE, WE, XE
(g, j, m, o, p)		ZINC IONnon-polymer65.45Chemie (ZN)
Sequence modifications
x: 1 - 504 (UniProt: P61011)
PDBExternal DatabaseDetails
Glu 226Gly 226engineered mutation
c: 1 - 115 (UniProt: G1TDL2)
PDBExternal DatabaseDetails
Thr 34Ser 34conflict
E: -5 - 284 (UniProt: G1SKF7)
PDBExternal DatabaseDetails
Arg 126Lys 133conflict
Gln 217Lys 224conflict
F: 26 - 250 (UniProt: G1SV32)
PDBExternal DatabaseDetails
Ala 175Thr 174conflict
Gly 185Asn 184conflict
Arg 202His 201conflict
Glu 233Gly 232conflict
L: 2 - 211 (UniProt: G1TPV0)
PDBExternal DatabaseDetails
Ala 47-insertion
Pro 48-insertion
Arg 49-insertion
Pro 50-insertion
Ala 51-insertion
Ser 52-insertion
Gly 53-insertion
Pro 54-insertion
Leu 55-insertion
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains52
Total formula weight2744677.8
Non-Polymers*Number of molecules102
Total formula weight2684.6
All*Total formula weight2747362.4
*Water molecules are not included.

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PDB entries from 2025-06-11

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