7QWF
BAZ2A bromodomain in complex with acetylpyrrole derivative compound 45
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain adjacent to zinc finger domain protein 2A | polymer | 105 | 12380.9 | 1 | UniProt (Q9UIF9) Pfam (PF00439) In PDB | Homo sapiens (human) | Transcription termination factor I-interacting protein 5,Tip5,hWALp3 |
| 2 | A | 1-[4-ethyl-2-methyl-5-[2-[2-(methylamino)ethyl]-1,3-thiazol-4-yl]-1~{H}-pyrrol-3-yl]ethanone | non-polymer | 291.4 | 1 | Chemie (FS6) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | water | water | 18.0 | 55 | Chemie (HOH) |
Sequence modifications
A: 1796 - 1898 (UniProt: Q9UIF9)
| PDB | External Database | Details |
|---|---|---|
| Ser 1794 | - | expression tag |
| Met 1795 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12380.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 439.9 | |
| All* | Total formula weight | 12820.8 |
