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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7QVP

Human collided disome (di-ribosome) stalled on XBP1 mRNA

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A4mRNApolymer144241.41Homo sapiens
2A5mRNApolymer113322.91Homo sapiens (human)
3B4, D5tRNA P/Ppolymer7624485.52GenBank (1850337400)Homo sapiens (human)
4B5tRNA P/Epolymer7524231.51GenBank (174924)Homo sapiens (human)
5CCtNRA E/Epolymer7524004.31GenBank (176418)Homo sapiens (human)
6L1, L85.8S ribosomal RNApolymer15750449.82GenBank (555853)Homo sapiens (human)
7L5, L628S ribosomal RNApolymer52271690723.52Homo sapiens (human)
8L7, L95S ribosomal RNApolymer12138998.12GenBank (23898)Homo sapiens (human)
9LA, MA60S ribosomal protein L8polymer25728088.92UniProt (A0A8B8VPA8)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL2
10LB, MB60S ribosomal protein L3polymer40346211.12UniProt (P39023)
Pfam (PF00297)
In PDB		Homo sapiens (human)HIV-1 TAR RNA-binding protein B,TARBP-B,Large ribosomal subunit protein uL3
11LC, MC60S ribosomal protein L4polymer42747804.62UniProt (P36578)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Homo sapiens (human)60S ribosomal protein L1,Large ribosomal subunit protein uL4
12LD, MD60S ribosomal protein L5polymer29734426.82UniProt (P46777)
Pfam (PF17144)
Pfam (PF14204)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL18
13LE, ME60S ribosomal protein L6polymer28832810.22UniProt (Q02878)
Pfam (PF03868)
Pfam (PF01159)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107
14LF, MF60S ribosomal protein L7polymer24829291.02UniProt (P18124)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL30
15LG, MG60S ribosomal protein L7apolymer26630061.82UniProt (P62424)
Pfam (PF01248)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3
16LH, MH60S ribosomal protein L9polymer19221899.52UniProt (P32969)
Pfam (PF00347)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL6
17LI, MI60S ribosomal protein L10-likepolymer21424570.92UniProt (Q96L21)
Pfam (PF00252)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL16-like
18LJ, MJ60S ribosomal protein L11polymer17820288.52UniProt (P62913)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Homo sapiens (human)CLL-associated antigen KW-12,Large ribosomal subunit protein uL5
19LL, ML60S ribosomal protein L13polymer21124321.72UniProt (P26373)
Pfam (PF01294)
In PDB		Homo sapiens (human)Breast basic conserved protein 1,Large ribosomal subunit protein eL13
20LM, MM60S ribosomal protein L14polymer21523485.02UniProt (P50914)
Pfam (PF01929)
In PDB		Homo sapiens (human)CAG-ISL 7,Large ribosomal subunit protein eL14
21LN, MN60S ribosomal protein L15polymer20424207.32UniProt (L8Y0W1)
Pfam (PF00827)
In PDB		Homo sapiens (human)
22LO, MO60S ribosomal protein L13apolymer20323633.42UniProt (P40429)
Pfam (PF00572)
In PDB		Homo sapiens (human)23 kDa highly basic protein,Large ribosomal subunit protein uL13
23LP60S ribosomal protein L17polymer15417888.81UniProt (P18621)
Pfam (PF00237)
In PDB		Homo sapiens (human)60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1
24LQ, MQ60S ribosomal protein L18polymer18821687.72UniProt (Q07020)
Pfam (PF17135)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL18
25LR, MR60S ribosomal protein L19polymer19623535.32UniProt (A0A2J8KH59)
Pfam (PF01280)
In PDB		Homo sapiens (human)
26LS, MS60S ribosomal protein L18apolymer17620808.52UniProt (Q02543)
Pfam (PF01775)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL20
27LT, MT60S ribosomal protein L21polymer16018610.02UniProt (P46778)
Pfam (PF01157)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL21
28LU, MU60S ribosomal protein L22polymer12814813.02UniProt (P35268)
Pfam (PF01776)
In PDB		Homo sapiens (human)EBER-associated protein,EAP,Epstein-Barr virus small RNA-associated protein,Heparin-binding protein HBp15,Large ribosomal subunit protein eL22
29LV, MV60S ribosomal protein L23polymer14014892.52UniProt (A0A3P9HH38)
Pfam (PF00238)
In PDB		Homo sapiens (human)
30LW, MW60S ribosomal protein L24polymer15717825.12UniProt (F2X267)
Pfam (PF01246)
In PDB		Homo sapiens (human)Ribosomal protein L24
31LX, MX60S ribosomal protein L23apolymer15617740.22UniProt (P62750)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL23
32LY, MYKOW domain-containing proteinpolymer14517303.42UniProt (A0A5N3X333)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Homo sapiens (human)
33LZ, MZ60S ribosomal protein L27polymer13615835.82UniProt (A0A851LWS6)
Pfam (PF00467)
Pfam (PF01777)
In PDB		Homo sapiens (human)
34La, Ma60S ribosomal protein L27apolymer14816604.52UniProt (P46776)
Pfam (PF00828)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL15
35Lb, Mb60S ribosomal protein L29polymer15917804.32UniProt (P47914)
Pfam (PF01779)
In PDB		Homo sapiens (human)Cell surface heparin-binding protein HIP,Large ribosomal subunit protein eL29
36Lc, Mc60S ribosomal protein L30polymer11512805.12UniProt (P62888)
Pfam (PF01248)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL30
37Ld, Md60S ribosomal protein L31polymer12514494.92UniProt (G7NZE1)
Pfam (PF01198)
In PDB		Homo sapiens (human)
38Le, Me60S ribosomal protein L32polymer13515898.92UniProt (P62910)
Pfam (PF01655)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL32
39Lf, Mf60S ribosomal protein L35apolymer11012564.72UniProt (P18077)
Pfam (PF01247)
In PDB		Homo sapiens (human)Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33
40Lg, Mg60S ribosomal protein L34polymer11713326.12UniProt (A0A1U7T3M5)
Pfam (PF01199)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL34
41Lh, Mh60S ribosomal protein L35polymer12314593.62UniProt (P42766)
Pfam (PF00831)
In PDB		Homo sapiens (human)Large ribosomal subunit protein uL29
42Li, Mi60S ribosomal protein L36polymer10512290.92UniProt (Q9Y3U8)
Pfam (PF01158)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL36
43Lj, MjRibosomal protein L37polymer8810379.32UniProt (A0A2Y9RW09)
Pfam (PF01907)
In PDB		Homo sapiens (human)
44Lk, Mk60S ribosomal protein L38polymer708238.92UniProt (A0A1A7W9T9)
Pfam (PF01781)
In PDB		Homo sapiens (human)
45Ll, Ml60S ribosomal protein L39polymer516426.82UniProt (A0A7N4PFJ2)
Pfam (PF00832)
In PDB		Homo sapiens (human)
46Lm, MmUbiquitin-60S ribosomal protein L40polymer12814758.42UniProt (A0A8C8Y9V5)
Pfam (PF00240)
Pfam (PF01020)
In PDB		Homo sapiens (human)
47Ln, Mn60S ribosomal protein L41polymer253473.52UniProt (P62945)
Pfam (PF05162)
In PDB		Homo sapiens (human)HG12,Large ribosomal subunit protein eL41
48Lo, Mo60S ribosomal protein L36apolymer10612477.02UniProt (J3KQN4)
Pfam (PF00935)
In PDB		Homo sapiens (human)
49Lp, Mp60S ribosomal protein L37apolymer9210299.42UniProt (A0A6I9ZMF9)
Pfam (PF01780)
In PDB		Homo sapiens (human)
50Lr, Mr60S ribosomal protein L28polymer13715784.62UniProt (P46779)
Pfam (PF01778)
In PDB		Homo sapiens (human)Large ribosomal subunit protein eL28
51MP60S ribosomal protein L17polymer18421443.21UniProt (P18621)
Pfam (PF00237)
In PDB		Homo sapiens (human)60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1
52RA, SA40S ribosomal protein SApolymer29532883.92UniProt (P08865)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Homo sapiens (human)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2
53RB, SB40S ribosomal protein S3apolymer26430002.12UniProt (P61247)
Pfam (PF01015)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1
54RC, SC40S ribosomal protein S2polymer29331376.52UniProt (P15880)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Homo sapiens (human)40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5
55RD, SD40S ribosomal protein S3polymer24326729.42UniProt (P23396)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Homo sapiens (human)Small ribosomal subunit protein uS3
56RE, SE40S ribosomal protein S4, X isoformpolymer26329654.92UniProt (P62701)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Homo sapiens (human)SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4
57RF, SF40S ribosomal protein S5polymer20422913.52UniProt (A0A6J0Y1Z7)
Pfam (PF00177)
In PDB		Homo sapiens (human)
58RG, SG40S ribosomal protein S6polymer24928751.92UniProt (P62753)
Pfam (PF01092)
In PDB		Homo sapiens (human)Phosphoprotein NP33,Small ribosomal subunit protein eS6
59RH, SH40S ribosomal protein S7polymer19422168.92UniProt (P62082)
Pfam (PF01251)
In PDB		Homo sapiens (human)
60RI, SI40S ribosomal protein S8polymer20824263.42UniProt (P62241)
Pfam (PF01201)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS8
61RJ, SJ40S ribosomal protein S9polymer19422641.62UniProt (A0A6J0B498)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Homo sapiens (human)
62RK, SK40S ribosomal protein S10polymer16518933.82UniProt (P46783)
Pfam (PF03501)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS10
63RL, SL40S ribosomal protein S11polymer15818468.82UniProt (A0A8B8VW69)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Homo sapiens (human)
64RN, SN40S ribosomal protein S13polymer15117259.42UniProt (A0A663F1C0)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Homo sapiens (human)
65RO, SO40S ribosomal protein S14polymer15116302.82UniProt (A0A7L0BEC6)
Pfam (PF00411)
In PDB		Homo sapiens (human)
66RP, SP40S ribosomal protein S15polymer14517076.22UniProt (A0A2K6QL61)
Pfam (PF00203)
In PDB		Homo sapiens (human)
67RQ, SQ40S ribosomal protein S16polymer14616477.42UniProt (A0A4W2HV66)
Pfam (PF00380)
In PDB		Homo sapiens (human)
68RR, SR40S ribosomal protein S17polymer13515578.22UniProt (P08708)
Pfam (PF00833)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS17
69RS, SS40S ribosomal protein S18polymer15217759.82UniProt (H0WTR0)
Pfam (PF00416)
In PDB		Homo sapiens (human)
70RT, ST40S ribosomal protein S19polymer14516091.62UniProt (A0A2Y9E7Q1)
Pfam (PF01090)
In PDB		Homo sapiens (human)
71RU, SU40S ribosomal protein S20polymer11913398.82UniProt (P60868)
Pfam (PF00338)
In PDB		Homo sapiens (human)
72RV, SV40S ribosomal protein S21polymer839124.42UniProt (P63220)
Pfam (PF01249)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS21
73RW, SW40S ribosomal protein S15apolymer13014865.62UniProt (A0A2K5QKS6)
Pfam (PF00410)
In PDB		Homo sapiens (human)
74RX, SX40S ribosomal protein S23polymer14315844.72UniProt (A0A340WVW7)
Pfam (PF00164)
In PDB		Homo sapiens (human)
75RY, SY40S ribosomal protein S24polymer13315463.32UniProt (P62847)
Pfam (PF01282)
In PDB		Homo sapiens (human)Small ribosomal subunit protein eS24
76RZ, SZ40S ribosomal protein S25polymer12513776.22UniProt (A0A6J3IG71)
Pfam (PF03297)
In PDB		Homo sapiens (human)
77Ra, Sa40S ribosomal protein S26polymer10111619.82UniProt (A0A6J2NCX2)
Pfam (PF01283)
In PDB		Homo sapiens (human)
78Rb, Sb40S ribosomal protein S27polymer849480.22UniProt (A0A7J8BG50)
Pfam (PF01667)
In PDB		Homo sapiens (human)
79Rc, Sc40S ribosomal protein S28polymer697855.12UniProt (A0A3M0JHZ8)
Pfam (PF01200)
In PDB		Homo sapiens (human)
80Rd, Sd40S ribosomal protein S29polymer566690.82UniProt (A0A2J8WKD7)
Pfam (PF00253)
In PDB		Homo sapiens (human)
81Re, Se40S ribosomal protein S30polymer596668.92UniProt (A0A2K6U587)
Pfam (PF04758)
In PDB		Homo sapiens (human)
82Rf40S ribosomal protein S12polymer13214539.01UniProt (A0A671DUR2)
Pfam (PF01248)
In PDB		Homo sapiens (human)
83Rg, SgReceptor of activated protein C kinase 1polymer31735115.72UniProt (A0A2K6K8B0)
Pfam (PF00400)
In PDB		Homo sapiens (human)
84RhUbiquitin-40S ribosomal protein S27apolymer15618004.01UniProt (A0A8C0T835)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Homo sapiens (human)Ubiquitin carboxyl extension protein 80
85S2, S318S ribosomal RNApolymer1869602776.92GenBank (36162)Homo sapiens (human)
Sequence modifications
CC: 1 - 75 (GenBank: 176418)
PDBExternal DatabaseDetails
C 11U 11conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains162
Total formula weight7725763.0
All*Total formula weight7725763.0
*Water molecules are not included.

218853

PDB entries from 2024-04-24

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