7QVP
Human collided disome (di-ribosome) stalled on XBP1 mRNA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A4) | mRNA | polymer | 14 | 4241.4 | 1 | Homo sapiens | ||
| 2 | B (A5) | mRNA | polymer | 11 | 3322.9 | 1 | Homo sapiens (human) | ||
| 3 | C, F (B4, D5) | tRNA P/P | polymer | 76 | 24485.5 | 2 | GenBank (1850337400) | Homo sapiens (human) | |
| 4 | D (B5) | tRNA P/E | polymer | 75 | 24231.5 | 1 | GenBank (174924) | Homo sapiens (human) | |
| 5 | E (CC) | tNRA E/E | polymer | 75 | 24004.3 | 1 | GenBank (176418) | Homo sapiens (human) | |
| 6 | G, K (L1, L8) | 5.8S ribosomal RNA | polymer | 157 | 50449.8 | 2 | GenBank (555853) | Homo sapiens (human) | |
| 7 | H, I (L5, L6) | 28S ribosomal RNA | polymer | 5227 | 1690723.5 | 2 | Homo sapiens (human) | ||
| 8 | J, L (L7, L9) | 5S ribosomal RNA | polymer | 121 | 38998.1 | 2 | GenBank (23898) | Homo sapiens (human) | |
| 9 | CB, M (LA, MA) | 60S ribosomal protein L8 | polymer | 257 | 28088.9 | 2 | UniProt (A0A8B8VPA8) Pfam (PF00181) Pfam (PF03947) | Homo sapiens (human) | Large ribosomal subunit protein uL2 |
| 10 | DB, N (LB, MB) | 60S ribosomal protein L3 | polymer | 403 | 46211.1 | 2 | UniProt (P39023) Pfam (PF00297) | Homo sapiens (human) | HIV-1 TAR RNA-binding protein B,TARBP-B,Large ribosomal subunit protein uL3 |
| 11 | EB, O (LC, MC) | 60S ribosomal protein L4 | polymer | 427 | 47804.6 | 2 | UniProt (P36578) Pfam (PF00573) Pfam (PF14374) | Homo sapiens (human) | 60S ribosomal protein L1,Large ribosomal subunit protein uL4 |
| 12 | FB, P (LD, MD) | 60S ribosomal protein L5 | polymer | 297 | 34426.8 | 2 | UniProt (P46777) Pfam (PF17144) Pfam (PF14204) | Homo sapiens (human) | Large ribosomal subunit protein uL18 |
| 13 | GB, Q (LE, ME) | 60S ribosomal protein L6 | polymer | 288 | 32810.2 | 2 | UniProt (Q02878) Pfam (PF03868) Pfam (PF01159) | Homo sapiens (human) | Large ribosomal subunit protein eL6,Neoplasm-related protein C140,Tax-responsive enhancer element-binding protein 107,TaxREB107 |
| 14 | HB, R (LF, MF) | 60S ribosomal protein L7 | polymer | 248 | 29291.0 | 2 | UniProt (P18124) Pfam (PF08079) Pfam (PF00327) | Homo sapiens (human) | Large ribosomal subunit protein uL30 |
| 15 | IB, S (LG, MG) | 60S ribosomal protein L7a | polymer | 266 | 30061.8 | 2 | UniProt (P62424) Pfam (PF01248) | Homo sapiens (human) | Large ribosomal subunit protein eL8,PLA-X polypeptide,Surfeit locus protein 3 |
| 16 | JB, T (LH, MH) | 60S ribosomal protein L9 | polymer | 192 | 21899.5 | 2 | UniProt (P32969) Pfam (PF00347) | Homo sapiens (human) | Large ribosomal subunit protein uL6 |
| 17 | KB, U (LI, MI) | 60S ribosomal protein L10-like | polymer | 214 | 24570.9 | 2 | UniProt (Q96L21) Pfam (PF00252) | Homo sapiens (human) | Large ribosomal subunit protein uL16-like |
| 18 | LB, V (LJ, MJ) | 60S ribosomal protein L11 | polymer | 178 | 20288.5 | 2 | UniProt (P62913) Pfam (PF00281) Pfam (PF00673) | Homo sapiens (human) | CLL-associated antigen KW-12,Large ribosomal subunit protein uL5 |
| 19 | MB, W (LL, ML) | 60S ribosomal protein L13 | polymer | 211 | 24321.7 | 2 | UniProt (P26373) Pfam (PF01294) | Homo sapiens (human) | Breast basic conserved protein 1,Large ribosomal subunit protein eL13 |
| 20 | NB, X (LM, MM) | 60S ribosomal protein L14 | polymer | 215 | 23485.0 | 2 | UniProt (P50914) Pfam (PF01929) | Homo sapiens (human) | CAG-ISL 7,Large ribosomal subunit protein eL14 |
| 21 | OB, Y (LN, MN) | 60S ribosomal protein L15 | polymer | 204 | 24207.3 | 2 | UniProt (L8Y0W1) Pfam (PF00827) | Homo sapiens (human) | |
| 22 | PB, Z (LO, MO) | 60S ribosomal protein L13a | polymer | 203 | 23633.4 | 2 | UniProt (P40429) Pfam (PF00572) | Homo sapiens (human) | 23 kDa highly basic protein,Large ribosomal subunit protein uL13 |
| 23 | AA (LP) | 60S ribosomal protein L17 | polymer | 154 | 17888.8 | 1 | UniProt (P18621) Pfam (PF00237) | Homo sapiens (human) | 60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1 |
| 24 | BA, RB (LQ, MQ) | 60S ribosomal protein L18 | polymer | 188 | 21687.7 | 2 | UniProt (Q07020) Pfam (PF17135) | Homo sapiens (human) | Large ribosomal subunit protein eL18 |
| 25 | CA, SB (LR, MR) | 60S ribosomal protein L19 | polymer | 196 | 23535.3 | 2 | UniProt (A0A2J8KH59) Pfam (PF01280) | Homo sapiens (human) | |
| 26 | DA, TB (LS, MS) | 60S ribosomal protein L18a | polymer | 176 | 20808.5 | 2 | UniProt (Q02543) Pfam (PF01775) | Homo sapiens (human) | Large ribosomal subunit protein eL20 |
| 27 | EA, UB (LT, MT) | 60S ribosomal protein L21 | polymer | 160 | 18610.0 | 2 | UniProt (P46778) Pfam (PF01157) | Homo sapiens (human) | Large ribosomal subunit protein eL21 |
| 28 | FA, VB (LU, MU) | 60S ribosomal protein L22 | polymer | 128 | 14813.0 | 2 | UniProt (P35268) Pfam (PF01776) | Homo sapiens (human) | EBER-associated protein,EAP,Epstein-Barr virus small RNA-associated protein,Heparin-binding protein HBp15,Large ribosomal subunit protein eL22 |
| 29 | GA, WB (LV, MV) | 60S ribosomal protein L23 | polymer | 140 | 14892.5 | 2 | UniProt (A0A3P9HH38) Pfam (PF00238) | Homo sapiens (human) | |
| 30 | HA, XB (LW, MW) | 60S ribosomal protein L24 | polymer | 157 | 17825.1 | 2 | UniProt (F2X267) Pfam (PF01246) | Homo sapiens (human) | Ribosomal protein L24 |
| 31 | IA, YB (LX, MX) | 60S ribosomal protein L23a | polymer | 156 | 17740.2 | 2 | UniProt (P62750) Pfam (PF03939) Pfam (PF00276) | Homo sapiens (human) | Large ribosomal subunit protein uL23 |
| 32 | JA, ZB (LY, MY) | KOW domain-containing protein | polymer | 145 | 17303.4 | 2 | UniProt (A0A5N3X333) Pfam (PF16906) Pfam (PF00467) | Homo sapiens (human) | |
| 33 | AC, KA (LZ, MZ) | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 2 | UniProt (A0A851LWS6) Pfam (PF00467) Pfam (PF01777) | Homo sapiens (human) | |
| 34 | BC, LA (La, Ma) | 60S ribosomal protein L27a | polymer | 148 | 16604.5 | 2 | UniProt (P46776) Pfam (PF00828) | Homo sapiens (human) | Large ribosomal subunit protein uL15 |
| 35 | CC, MA (Lb, Mb) | 60S ribosomal protein L29 | polymer | 159 | 17804.3 | 2 | UniProt (P47914) Pfam (PF01779) | Homo sapiens (human) | Cell surface heparin-binding protein HIP,Large ribosomal subunit protein eL29 |
| 36 | DC, NA (Lc, Mc) | 60S ribosomal protein L30 | polymer | 115 | 12805.1 | 2 | UniProt (P62888) Pfam (PF01248) | Homo sapiens (human) | Large ribosomal subunit protein eL30 |
| 37 | EC, OA (Ld, Md) | 60S ribosomal protein L31 | polymer | 125 | 14494.9 | 2 | UniProt (G7NZE1) Pfam (PF01198) | Homo sapiens (human) | |
| 38 | FC, PA (Le, Me) | 60S ribosomal protein L32 | polymer | 135 | 15898.9 | 2 | UniProt (P62910) Pfam (PF01655) | Homo sapiens (human) | Large ribosomal subunit protein eL32 |
| 39 | GC, QA (Lf, Mf) | 60S ribosomal protein L35a | polymer | 110 | 12564.7 | 2 | UniProt (P18077) Pfam (PF01247) | Homo sapiens (human) | Cell growth-inhibiting gene 33 protein,Large ribosomal subunit protein eL33 |
| 40 | HC, RA (Lg, Mg) | 60S ribosomal protein L34 | polymer | 117 | 13326.1 | 2 | UniProt (A0A1U7T3M5) Pfam (PF01199) | Homo sapiens (human) | Large ribosomal subunit protein eL34 |
| 41 | IC, SA (Lh, Mh) | 60S ribosomal protein L35 | polymer | 123 | 14593.6 | 2 | UniProt (P42766) Pfam (PF00831) | Homo sapiens (human) | Large ribosomal subunit protein uL29 |
| 42 | JC, TA (Li, Mi) | 60S ribosomal protein L36 | polymer | 105 | 12290.9 | 2 | UniProt (Q9Y3U8) Pfam (PF01158) | Homo sapiens (human) | Large ribosomal subunit protein eL36 |
| 43 | KC, UA (Lj, Mj) | Ribosomal protein L37 | polymer | 88 | 10379.3 | 2 | UniProt (A0A2Y9RW09) Pfam (PF01907) | Homo sapiens (human) | |
| 44 | LC, VA (Lk, Mk) | 60S ribosomal protein L38 | polymer | 70 | 8238.9 | 2 | UniProt (A0A1A7W9T9) Pfam (PF01781) | Homo sapiens (human) | |
| 45 | MC, WA (Ll, Ml) | 60S ribosomal protein L39 | polymer | 51 | 6426.8 | 2 | UniProt (A0A7N4PFJ2) Pfam (PF00832) | Homo sapiens (human) | |
| 46 | NC, XA (Lm, Mm) | Ubiquitin-60S ribosomal protein L40 | polymer | 128 | 14758.4 | 2 | UniProt (A0A8C8Y9V5) Pfam (PF00240) Pfam (PF01020) | Homo sapiens (human) | |
| 47 | OC, YA (Ln, Mn) | 60S ribosomal protein L41 | polymer | 25 | 3473.5 | 2 | UniProt (P62945) Pfam (PF05162) | Homo sapiens (human) | HG12,Large ribosomal subunit protein eL41 |
| 48 | PC, ZA (Lo, Mo) | 60S ribosomal protein L36a | polymer | 106 | 12477.0 | 2 | UniProt (J3KQN4) Pfam (PF00935) | Homo sapiens (human) | |
| 49 | AB, QC (Lp, Mp) | 60S ribosomal protein L37a | polymer | 92 | 10299.4 | 2 | UniProt (A0A6I9ZMF9) Pfam (PF01780) | Homo sapiens (human) | |
| 50 | BB, RC (Lr, Mr) | 60S ribosomal protein L28 | polymer | 137 | 15784.6 | 2 | UniProt (P46779) Pfam (PF01778) | Homo sapiens (human) | Large ribosomal subunit protein eL28 |
| 51 | QB (MP) | 60S ribosomal protein L17 | polymer | 184 | 21443.2 | 1 | UniProt (P18621) Pfam (PF00237) | Homo sapiens (human) | 60S ribosomal protein L23,Large ribosomal subunit protein uL22,PD-1 |
| 52 | BE, SC (RA, SA) | 40S ribosomal protein SA | polymer | 295 | 32883.9 | 2 | UniProt (P08865) Pfam (PF00318) Pfam (PF16122) | Homo sapiens (human) | 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Colon carcinoma laminin-binding protein,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40,Multidrug resistance-associated protein MGr1-Ag,NEM/1CHD4,Small ribosomal subunit protein uS2 |
| 53 | CE, TC (RB, SB) | 40S ribosomal protein S3a | polymer | 264 | 30002.1 | 2 | UniProt (P61247) Pfam (PF01015) | Homo sapiens (human) | Small ribosomal subunit protein eS1,v-fos transformation effector protein,Fte-1 |
| 54 | DE, UC (RC, SC) | 40S ribosomal protein S2 | polymer | 293 | 31376.5 | 2 | UniProt (P15880) Pfam (PF00333) Pfam (PF03719) | Homo sapiens (human) | 40S ribosomal protein S4,Protein LLRep3,Small ribosomal subunit protein uS5 |
| 55 | EE, VC (RD, SD) | 40S ribosomal protein S3 | polymer | 243 | 26729.4 | 2 | UniProt (P23396) Pfam (PF07650) Pfam (PF00189) | Homo sapiens (human) | Small ribosomal subunit protein uS3 |
| 56 | FE, WC (RE, SE) | 40S ribosomal protein S4, X isoform | polymer | 263 | 29654.9 | 2 | UniProt (P62701) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121) | Homo sapiens (human) | SCR10,Single copy abundant mRNA protein,Small ribosomal subunit protein eS4 |
| 57 | GE, XC (RF, SF) | 40S ribosomal protein S5 | polymer | 204 | 22913.5 | 2 | UniProt (A0A6J0Y1Z7) Pfam (PF00177) | Homo sapiens (human) | |
| 58 | HE, YC (RG, SG) | 40S ribosomal protein S6 | polymer | 249 | 28751.9 | 2 | UniProt (P62753) Pfam (PF01092) | Homo sapiens (human) | Phosphoprotein NP33,Small ribosomal subunit protein eS6 |
| 59 | IE, ZC (RH, SH) | 40S ribosomal protein S7 | polymer | 194 | 22168.9 | 2 | UniProt (P62082) Pfam (PF01251) | Homo sapiens (human) | |
| 60 | AD, JE (RI, SI) | 40S ribosomal protein S8 | polymer | 208 | 24263.4 | 2 | UniProt (P62241) Pfam (PF01201) | Homo sapiens (human) | Small ribosomal subunit protein eS8 |
| 61 | BD, KE (RJ, SJ) | 40S ribosomal protein S9 | polymer | 194 | 22641.6 | 2 | UniProt (A0A6J0B498) Pfam (PF00163) Pfam (PF01479) | Homo sapiens (human) | |
| 62 | CD, LE (RK, SK) | 40S ribosomal protein S10 | polymer | 165 | 18933.8 | 2 | UniProt (P46783) Pfam (PF03501) | Homo sapiens (human) | Small ribosomal subunit protein eS10 |
| 63 | DD, ME (RL, SL) | 40S ribosomal protein S11 | polymer | 158 | 18468.8 | 2 | UniProt (A0A8B8VW69) Pfam (PF16205) Pfam (PF00366) | Homo sapiens (human) | |
| 64 | ED, NE (RN, SN) | 40S ribosomal protein S13 | polymer | 151 | 17259.4 | 2 | UniProt (A0A663F1C0) Pfam (PF08069) Pfam (PF00312) | Homo sapiens (human) | |
| 65 | FD, OE (RO, SO) | 40S ribosomal protein S14 | polymer | 151 | 16302.8 | 2 | UniProt (A0A7L0BEC6) Pfam (PF00411) | Homo sapiens (human) | |
| 66 | GD, PE (RP, SP) | 40S ribosomal protein S15 | polymer | 145 | 17076.2 | 2 | UniProt (A0A2K6QL61) Pfam (PF00203) | Homo sapiens (human) | |
| 67 | HD, QE (RQ, SQ) | 40S ribosomal protein S16 | polymer | 146 | 16477.4 | 2 | UniProt (A0A4W2HV66) Pfam (PF00380) | Homo sapiens (human) | |
| 68 | ID, RE (RR, SR) | 40S ribosomal protein S17 | polymer | 135 | 15578.2 | 2 | UniProt (P08708) Pfam (PF00833) | Homo sapiens (human) | Small ribosomal subunit protein eS17 |
| 69 | JD, SE (RS, SS) | 40S ribosomal protein S18 | polymer | 152 | 17759.8 | 2 | UniProt (H0WTR0) Pfam (PF00416) | Homo sapiens (human) | |
| 70 | KD, TE (RT, ST) | 40S ribosomal protein S19 | polymer | 145 | 16091.6 | 2 | UniProt (A0A2Y9E7Q1) Pfam (PF01090) | Homo sapiens (human) | |
| 71 | LD, UE (RU, SU) | 40S ribosomal protein S20 | polymer | 119 | 13398.8 | 2 | UniProt (P60868) Pfam (PF00338) | Homo sapiens (human) | |
| 72 | MD, VE (RV, SV) | 40S ribosomal protein S21 | polymer | 83 | 9124.4 | 2 | UniProt (P63220) Pfam (PF01249) | Homo sapiens (human) | Small ribosomal subunit protein eS21 |
| 73 | ND, WE (RW, SW) | 40S ribosomal protein S15a | polymer | 130 | 14865.6 | 2 | UniProt (A0A2K5QKS6) Pfam (PF00410) | Homo sapiens (human) | |
| 74 | OD, XE (RX, SX) | 40S ribosomal protein S23 | polymer | 143 | 15844.7 | 2 | UniProt (A0A340WVW7) Pfam (PF00164) | Homo sapiens (human) | |
| 75 | PD, YE (RY, SY) | 40S ribosomal protein S24 | polymer | 133 | 15463.3 | 2 | UniProt (P62847) Pfam (PF01282) | Homo sapiens (human) | Small ribosomal subunit protein eS24 |
| 76 | QD, ZE (RZ, SZ) | 40S ribosomal protein S25 | polymer | 125 | 13776.2 | 2 | UniProt (A0A6J3IG71) Pfam (PF03297) | Homo sapiens (human) | |
| 77 | AF, RD (Ra, Sa) | 40S ribosomal protein S26 | polymer | 101 | 11619.8 | 2 | UniProt (A0A6J2NCX2) Pfam (PF01283) | Homo sapiens (human) | |
| 78 | BF, SD (Rb, Sb) | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 2 | UniProt (A0A7J8BG50) Pfam (PF01667) | Homo sapiens (human) | |
| 79 | CF, TD (Rc, Sc) | 40S ribosomal protein S28 | polymer | 69 | 7855.1 | 2 | UniProt (A0A3M0JHZ8) Pfam (PF01200) | Homo sapiens (human) | |
| 80 | DF, UD (Rd, Sd) | 40S ribosomal protein S29 | polymer | 56 | 6690.8 | 2 | UniProt (A0A2J8WKD7) Pfam (PF00253) | Homo sapiens (human) | |
| 81 | EF, VD (Re, Se) | 40S ribosomal protein S30 | polymer | 59 | 6668.9 | 2 | UniProt (A0A2K6U587) Pfam (PF04758) | Homo sapiens (human) | |
| 82 | WD (Rf) | 40S ribosomal protein S12 | polymer | 132 | 14539.0 | 1 | UniProt (A0A671DUR2) Pfam (PF01248) | Homo sapiens (human) | |
| 83 | FF, XD (Rg, Sg) | Receptor of activated protein C kinase 1 | polymer | 317 | 35115.7 | 2 | UniProt (A0A2K6K8B0) Pfam (PF00400) | Homo sapiens (human) | |
| 84 | YD (Rh) | Ubiquitin-40S ribosomal protein S27a | polymer | 156 | 18004.0 | 1 | UniProt (A0A8C0T835) Pfam (PF00240) Pfam (PF01599) | Homo sapiens (human) | Ubiquitin carboxyl extension protein 80 |
| 85 | AE, ZD (S2, S3) | 18S ribosomal RNA | polymer | 1869 | 602776.9 | 2 | GenBank (36162) | Homo sapiens (human) |
Sequence modifications
CC: 1 - 75 (GenBank: 176418)
| PDB | External Database | Details |
|---|---|---|
| C 11 | U 11 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 162 |
| Total formula weight | 7725763.0 | |
| All* | Total formula weight | 7725763.0 |
