7QVL
OESTROGEN RECEPTOR LIGAND BINDING DOMAIN IN COMPLEX WITH COMPOUND 38
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Estrogen receptor | polymer | 252 | 28655.5 | 2 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
| 2 | A, B | (2~{R})-3-[(1~{R},3~{R})-1-[5-fluoranyl-2-[2-(3-fluoranylpropylamino)ethoxy]-3-methyl-pyridin-4-yl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-2-methyl-propanoic acid | non-polymer | 500.6 | 2 | Chemie (GZI) | |||
| 3 | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, B: 307 - 554 (UniProt: P03372)
| PDB | External Database | Details |
|---|---|---|
| Gly 303 | - | expression tag |
| Ser 304 | - | expression tag |
| His 305 | - | expression tag |
| Met 306 | - | expression tag |
| Ser 381 | Cys 381 | engineered mutation |
| Ser 417 | Cys 417 | engineered mutation |
| Ser 530 | Cys 530 | engineered mutation |
| Ser 536 | Leu 536 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57311.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1001.2 | |
| All* | Total formula weight | 58312.2 |
