7QVJ
ESTROGEN RECEPTOR ALPHA IN COMPLEX WITH COMPOUND 29
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Estrogen receptor | polymer | 252 | 28655.5 | 2 | UniProt (P03372) Pfam (PF00104) In PDB | Homo sapiens (human) | ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1 |
2 | A, B | 2,2-bis(fluoranyl)-3-[(1~{R},3~{R})-1-[6-fluoranyl-3-[2-(3-fluoranylpropylamino)ethoxy]-2-methyl-phenyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]propan-1-ol | non-polymer | 507.6 | 2 | Chemie (H09) | |||
3 | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence modifications
A, B: 307 - 554 (UniProt: P03372)
PDB | External Database | Details |
---|---|---|
Gly 303 | - | expression tag |
Ser 304 | - | expression tag |
His 305 | - | expression tag |
Met 306 | - | expression tag |
Ser 381 | Cys 381 | engineered mutation |
Ser 417 | Cys 417 | engineered mutation |
Ser 530 | Cys 530 | engineered mutation |
Ser 536 | Leu 536 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 57311.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 1015.1 | |
All* | Total formula weight | 58326.2 |