7QU6

Crystal structure of the N-terminal domain of Siglec-8

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (B, A, C, D, E...)	Sialic acid-binding Ig-like lectin 8	polymer	153	17638.5	6	UniProt (Q9NYZ4) Pfam (PF07686)	Homo sapiens (human)	Siglec-8,Sialoadhesin family member 2,SAF-2
2	G, H, I, J, K... (B, A, C, D, E...)	water	water		18.0	305	Chemie (HOH)

Sequence modifications

B, A, C, D, E, F: 17 - 155 (UniProt: Q9NYZ4)

PDB	External Database	Details
Ser 42	Cys 42	conflict
Gly 156	-	expression tag
Ser 157	-	expression tag
Leu 158	-	expression tag
Val 159	-	expression tag
Pro 160	-	expression tag
Arg 161	-	expression tag
Gly 162	-	expression tag
Ser 163	-	expression tag
His 164	-	expression tag
His 165	-	expression tag
His 166	-	expression tag
His 167	-	expression tag
His 168	-	expression tag
His 169	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	105830.8
All*	Total formula weight	105830.8

*Water molecules are not included.