7QU4
Recombinant Human Fetal Hemoglobin mutant - alpha subunit mutations K11E,K56E,N78D,K90E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | G, H | Hemoglobin subunit gamma-2 | polymer | 147 | 16148.4 | 2 | UniProt (P69892) Pfam (PF00042) In PDB | Homo sapiens (human) | Gamma-2-globin,Hb F Ggamma,Hemoglobin gamma-2 chain,Hemoglobin gamma-G chain |
| 2 | A, B | Hemoglobin subunit alpha | polymer | 142 | 15282.3 | 2 | UniProt (P69905) Pfam (PF00042) In PDB | Homo sapiens (human) | Alpha-globin,Hemoglobin alpha chain |
| 3 | G, H, A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 4 | water | water | 18.0 | 565 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 142 (UniProt: P69905)
| PDB | External Database | Details |
|---|---|---|
| Glu 12 | Lys 12 | engineered mutation |
| Glu 57 | Lys 57 | engineered mutation |
| Asp 79 | Asn 79 | engineered mutation |
| Glu 91 | Lys 91 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62861.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 2465.9 | |
| All* | Total formula weight | 65327.5 |
