7QRA
Crystal structure of CK1 delta in complex with VN725
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Casein kinase I isoform delta | polymer | 296 | 34424.8 | 4 | UniProt (P48730) Pfam (PF00069) | Homo sapiens (human) | CKId,Tau-protein kinase CSNK1D |
| 2 | E, F, G, L, M... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 10 | Chemie (SO4) | |||
| 3 | AA, H, I, J, O... (D, A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 10 | Chemie (EDO) | |||
| 4 | BA, K, S, X (D, A, B, C) | 4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]-1~{H}-pyrrolo[2,3-b]pyridine | non-polymer | 360.4 | 4 | Chemie (EYI) | |||
| 5 | CA, DA, EA, FA (A, B, C, D) | water | water | 18.0 | 333 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 294 (UniProt: P48730)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 137699.2 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 3023.0 | |
| All* | Total formula weight | 140722.2 |
