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7QQM

The PDZ domain of LRRC7 fused with ANXA2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Leucine-rich repeat-containing protein 7,Annexin A2polymer41446845.31UniProt (Q96NW7)
UniProt (P07355)
Pfam (PF00595)
Pfam (PF00191)
Homo sapiens (human)Densin-180,Densin,Protein LAP1,Annexin II,Annexin-2,Calpactin I heavy chain,Calpactin-1 heavy chain,Chromobindin-8,Lipocortin II,Placental anticoagulant protein IV,PAP-IV,Protein I,p36
2B, C, D, E
(A)
CALCIUM IONnon-polymer40.14Chemie (CA)
3F, G, H
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
4I
(A)
waterwater18.0499Chemie (HOH)
Sequence modifications
A: 1445 - 1536 (UniProt: Q96NW7)
PDBExternal DatabaseDetails
His 1442-expression tag
Met 1443-expression tag
Gly 1444-expression tag
Gly 1537-linker
Ser 1538-linker
A: 1539 - 1855 (UniProt: P07355)
PDBExternal DatabaseDetails
Glu 1582Ala 66engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight46845.3
Non-Polymers*Number of molecules7
Total formula weight436.6
All*Total formula weight47281.9
*Water molecules are not included.

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PDB entries from 2024-11-06

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