7QQL

The PDZ domain of SNTG2 complexed with the phosphorylated PDZ-binding motif of RSK1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, D (C, A, B)	Gamma-2-syntrophin,Annexin A2	polymer	408	46138.4	3	UniProt (Q9NY99) UniProt (P07355) Pfam (PF00595) Pfam (PF00191)	Homo sapiens (human)	G2SYN,Syntrophin-5,SYN5,Annexin II,Annexin-2,Calpactin I heavy chain,Calpactin-1 heavy chain,Chromobindin-8,Lipocortin II,Placental anticoagulant protein IV,PAP-IV,Protein I,p36
2	B, E, F (F, D, E)	Ribosomal protein S6 kinase alpha-1	polymer	11	1410.6	3	UniProt (Q15418)	Homo sapiens	S6K-alpha-1,90 kDa ribosomal protein S6 kinase 1,p90-RSK 1,p90RSK1,p90S6K,MAP kinase-activated protein kinase 1a,MAPK-activated protein kinase 1a,MAPKAP kinase 1a,MAPKAPK-1a,Ribosomal S6 kinase 1,RSK-1
3	G, H, I, J, K... (C, A, B)	CALCIUM ION	non-polymer		40.1	14	Chemie (CA)
4	L, Q, W (C, A, B)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
5	X, Y, Z (C, A, B)	water	water		18.0	223	Chemie (HOH)

Sequence modifications

C, A, B: 70 - 159 (UniProt: Q9NY99)

PDB	External Database	Details
Gly 65	-	expression tag
Ser 66	-	expression tag
His 67	-	expression tag
Met 68	-	expression tag
Gly 69	-	expression tag
Gly 160	-	linker
Ser 161	-	linker

C, A, B: 162 - 472 (UniProt: P07355)

PDB	External Database	Details
Glu 199	Ala 66	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	142646.9
Non-Polymers*	Number of molecules	17
	Total formula weight	837.4
All*	Total formula weight	143484.2

*Water molecules are not included.