7QPU
Botulinum neurotoxin A5 cell binding domain in complex with GM1b oligosaccharide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Botulinum neurotoxin sub-type A5 | polymer | 433 | 50719.4 | 2 | UniProt (C1IPK2) Pfam (PF07953) Pfam (PF07951) In PDB | Clostridium botulinum | CntA/A5 |
| 2 | C | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose | branched | 471.4 | 1 | In PDB GlyTouCan (G30207PZ) | |||
| 3 | B | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A, B: 871 - 1296 (UniProt: C1IPK2)
| PDB | External Database | Details |
|---|---|---|
| Met 864 | - | initiating methionine |
| His 865 | - | expression tag |
| His 866 | - | expression tag |
| His 867 | - | expression tag |
| His 868 | - | expression tag |
| His 869 | - | expression tag |
| His 870 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 101438.8 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 471.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 202.2 | |
| All* | Total formula weight | 102112.4 |
