7QPN
Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) | polymer | 348 | 40148.9 | 2 | Pfam (PF01504) UniProt (by SIFTS) (Q8TBX8) | Homo sapiens | |
| 2 | C, F (A, B) | 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine | non-polymer | 357.5 | 2 | Chemie (DVF) PubChem (163321784) | |||
| 3 | D, E (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 80297.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1727.3 | |
| All* | Total formula weight | 82025.1 |
