7QPN

Crystal Structure of Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C) bound to an allosteric inhibitor and AMP-PNP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4K2C)	polymer	348	40148.9	2	Pfam (PF01504) UniProt (by SIFTS) (Q8TBX8) In PDB	Homo sapiens
2	A, B	5-methyl-2-(2-propan-2-ylphenyl)-~{N}-(pyridin-2-ylmethyl)pyrrolo[3,2-d]pyrimidin-4-amine	non-polymer		357.5	2	Chemie (DVF)
3	A, B	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	2	Chemie (ANP)
4		water	water		18.0	210	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	80297.8
Non-Polymers*	Number of molecules	4
	Total formula weight	1727.3
All*	Total formula weight	82025.1

*Water molecules are not included.