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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7QO5

26S proteasome Rpt1-RK -Ubp6-UbVS complex in the si state

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1a, AProteasome subunit alpha type-1polymer25228033.82UniProt (P21243)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein
2b, BProteasome subunit alpha type-2polymer25027191.82UniProt (P23639)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7
3c, CProteasome subunit alpha type-3polymer25828748.22UniProt (P23638)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13
4d, DProteasome subunit alpha type-4polymer25428478.12UniProt (P40303)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6
5e, EProteasome subunit alpha type-5polymer26028649.12UniProt (P32379)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2
6f, FProteasome subunit alpha type-6polymer23425634.02UniProt (P40302)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5
7g, GProbable proteasome subunit alpha type-7polymer28831575.12UniProt (P21242)
Pfam (PF10584)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1
8h, 1Proteasome subunit beta type-1polymer21523573.62UniProt (P38624)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3
9i, 2Proteasome subunit beta type-2polymer26128299.92UniProt (P25043)
Pfam (PF00227)
Pfam (PF12465)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1
10j, 3Proteasome subunit beta type-3polymer20522627.82UniProt (P25451)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3
11k, 4Proteasome subunit beta type-4polymer19822545.72UniProt (P22141)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11
12l, 5Proteasome subunit beta type-5polymer28731670.52UniProt (P30656)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2
13m, 6Proteasome subunit beta type-6polymer24126905.12UniProt (P23724)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Multicatalytic endopeptidase complex subunit C5,Proteasome component C5
14n, 7Proteasome subunit beta type-7polymer26629471.32UniProt (P30657)
Pfam (PF00227)
In PDB		Saccharomyces cerevisiae (baker's yeast)Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4
15W26S proteasome regulatory subunit RPN10polymer26829776.11UniProt (P38886)
Pfam (PF13519)
In PDB		Saccharomyces cerevisiae (baker's yeast)
16VUbiquitin carboxyl-terminal hydrolase RPN11polymer30634442.31UniProt (P43588)
Pfam (PF01398)
In PDB		Saccharomyces cerevisiae (baker's yeast)26S proteasome regulatory subunit RPN11,Protein MPR1
17T26S proteasome regulatory subunit RPN12polymer27431952.11UniProt (P32496)
Pfam (PF10075)
In PDB		Saccharomyces cerevisiae (baker's yeast)Nuclear integrity protein 1
18X26S proteasome regulatory subunit RPN13polymer15617919.01UniProt (O13563)
Pfam (PF04683)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome non-ATPase subunit 13
19Y26S proteasome complex subunit SEM1polymer8910397.11UniProt (O94742)
Pfam (PF05160)
In PDB		Saccharomyces cerevisiae (baker's yeast)
20Z26S proteasome regulatory subunit RPN1polymer993109601.91UniProt (P38764)
Pfam (PF17781)
Pfam (PF01851)
Pfam (PF18051)
In PDB		Saccharomyces cerevisiae (baker's yeast)HMG-CoA reductase degradation protein 2,Proteasome non-ATPase subunit 1
21N26S proteasome regulatory subunit RPN2polymer945104351.91UniProt (P32565)
Pfam (PF21505)
Pfam (PF01851)
Pfam (PF13646)
Pfam (PF18004)
In PDB		Saccharomyces cerevisiae (baker's yeast)
22S26S proteasome regulatory subunit RPN3polymer52360464.61UniProt (P40016)
Pfam (PF01399)
Pfam (PF08375)
In PDB		Saccharomyces cerevisiae (baker's yeast)
23P26S proteasome regulatory subunit RPN5polymer44551840.41UniProt (Q12250)
Pfam (PF22241)
Pfam (PF01399)
Pfam (PF18098)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome non-ATPase subunit 5
24Q26S proteasome regulatory subunit RPN6polymer43449839.81UniProt (Q12377)
Pfam (PF18055)
Pfam (PF01399)
Pfam (PF18503)
In PDB		Saccharomyces cerevisiae (baker's yeast)Proteasome non-ATPase subunit 4
25R26S proteasome regulatory subunit RPN7polymer42949016.41UniProt (Q06103)
Pfam (PF10602)
Pfam (PF01399)
Pfam (PF21154)
In PDB		Saccharomyces cerevisiae (baker's yeast)
26U26S proteasome regulatory subunit RPN8polymer33838365.51UniProt (Q08723)
Pfam (PF01398)
Pfam (PF13012)
In PDB		Saccharomyces cerevisiae (baker's yeast)
27O26S proteasome regulatory subunit RPN9polymer39345839.31UniProt (Q04062)
Pfam (PF22037)
Pfam (PF01399)
Pfam (PF18261)
In PDB		Saccharomyces cerevisiae (baker's yeast)
28H26S proteasome regulatory subunit 7 homologpolymer46752153.11UniProt (P33299)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)Protein CIM5,Tat-binding homolog 3
29I26S proteasome regulatory subunit 4 homologpolymer43748898.21UniProt (P40327)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)Tat-binding homolog 5
30K26S proteasome regulatory subunit 6B homologpolymer42847953.71UniProt (P33298)
Pfam (PF16450)
Pfam (PF00004)
In PDB		Saccharomyces cerevisiae (baker's yeast)Protein YNT1,Tat-binding homolog 2
31L26S proteasome subunit RPT4polymer43749480.11UniProt (P53549)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)26S protease subunit SUG2,Proteasomal cap subunit
32M26S proteasome regulatory subunit 6Apolymer43448315.71UniProt (P33297)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)Tat-binding protein homolog 1,TBP-1
33J26S proteasome regulatory subunit 8 homologpolymer40545342.71UniProt (Q01939)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		Saccharomyces cerevisiae (baker's yeast)Protein CIM3,Protein SUG1,Tat-binding protein TBY1
348Ubiquitin carboxyl-terminal hydrolase 6polymer49957188.61UniProt (P43593)
Pfam (PF00443)
In PDB		Saccharomyces cerevisiae (baker's yeast)Deubiquitinating enzyme 6,Ubiquitin thioesterase 6,Ubiquitin-specific-processing protease 6
359Polyubiquitin-Bpolymer768560.81UniProt (P0CG47)
Pfam (PF00240)
In PDB		Homo sapiens (human)
36K, L, M, H, IADENOSINE-5'-TRIPHOSPHATEnon-polymer507.25Chemie (ATP)
37I, K, L, M, J...MAGNESIUM IONnon-polymer24.36Chemie (MG)
38JADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
Sequence modifications
H: 1 - 467 (UniProt: P33299)
PDBExternal DatabaseDetails
Arg 164Ser 164variant
Lys 166Thr 166variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains49
Total formula weight1758507.5
Non-Polymers*Number of molecules12
Total formula weight3108.9
All*Total formula weight1761616.5
*Water molecules are not included.

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PDB entries from 2024-07-24

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