7QNO

Crystal structure of ligand-free Danio rerio HDAC6 CD1 CD2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Histone deacetylase 6	polymer	837	91951.2	1	UniProt (F8W4B7) Pfam (PF00850)	Danio rerio (zebrafish)
2	B (A)	PROLINE	non-polymer		115.1	1	Chemie (PRO)
3	C, D, F, G (A)	POTASSIUM ION	non-polymer		39.1	4	Chemie (K)
4	E (A)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
5	H, I, J, K, L... (A)	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
6	N (A)	water	water		18.0	17	Chemie (HOH)

Sequence modifications

A: 40 - 831 (UniProt: F8W4B7)

PDB	External Database	Details
Met -5	-	initiating methionine
Asp -4	-	expression tag
Ser -3	-	expression tag
Ala -2	-	expression tag
Trp -1	-	expression tag
Ser 0	-	expression tag
His 1	-	expression tag
Pro 2	-	expression tag
Gln 3	-	expression tag
Phe 4	-	expression tag
Glu 5	-	expression tag
Lys 6	-	expression tag
Gly 7	-	expression tag
Gly 8	-	expression tag
Gly 9	-	expression tag
Ser 10	-	expression tag
Gly 11	-	expression tag
Gly 12	-	expression tag
Gly 13	-	expression tag
Ser 14	-	expression tag
Gly 15	-	expression tag
Gly 16	-	expression tag
Ser 17	-	expression tag
Ala 18	-	expression tag
Trp 19	-	expression tag
Ser 20	-	expression tag
His 21	-	expression tag
Pro 22	-	expression tag
Gln 23	-	expression tag
Phe 24	-	expression tag
Glu 25	-	expression tag
Lys 26	-	expression tag
Ser 27	-	expression tag
Ala 28	-	expression tag
Val 29	-	expression tag
Asp 30	-	expression tag
Leu 31	-	expression tag
Glu 32	-	expression tag
Val 33	-	expression tag
Leu 34	-	expression tag
Phe 35	-	expression tag
Gln 36	-	expression tag
Gly 37	-	expression tag
Pro 38	-	expression tag
Gly 39	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	91951.2
Non-Polymers*	Number of molecules	12
	Total formula weight	889.5
All*	Total formula weight	92840.7

*Water molecules are not included.