7QLP
Structure of beta-lactamase TEM-171 complexed with tazobactam intermediate at 2.3 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Beta-lactamase TEM | polymer | 263 | 28956.0 | 6 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | IRT-4,Penicillinase,TEM-1,TEM-16/CAZ-7,TEM-2,TEM-24/CAZ-6,TEM-3,TEM-4,TEM-5,TEM-6,TEM-8/CAZ-2 |
| 2 | G, J, K, M (A, C, D, E) | TAZOBACTAM INTERMEDIATE | non-polymer | 302.3 | 4 | Chemie (TBE) | |||
| 3 | H (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | I (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | L (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | N, O, P, Q, R... (A, B, C, D, E...) | water | water | 18.0 | 828 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 26 - 288 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Ile 84 | Val 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 173736.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1452.5 | |
| All* | Total formula weight | 175188.6 |
