7QLP
Structure of beta-lactamase TEM-171 complexed with tazobactam intermediate at 2.3 A resolution
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Beta-lactamase TEM | polymer | 263 | 28956.0 | 6 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) In PDB | Escherichia coli | IRT-4,Penicillinase,TEM-1,TEM-16/CAZ-7,TEM-2,TEM-24/CAZ-6,TEM-3,TEM-4,TEM-5,TEM-6,TEM-8/CAZ-2 |
2 | A, C, D, E | TAZOBACTAM INTERMEDIATE | non-polymer | 302.3 | 4 | Chemie (TBE) | |||
3 | A | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
4 | A | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
5 | D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
6 | water | water | 18.0 | 828 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 26 - 288 (UniProt: P62593)
PDB | External Database | Details |
---|---|---|
Ile 84 | Val 82 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 173736.1 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 1452.5 | |
All* | Total formula weight | 175188.6 |