7QIK
SARS-CoV-2 Nucleocapsid phosphopeptide 193-200 bound to human 14-3-3 sigma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 14-3-3 protein sigma | polymer | 234 | 26257.6 | 2 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | C, D (E, F) | SER-SER-ARG-ASN-SEP-THR-PRO-GLY | polymer | 8 | 885.8 | 2 | UniProt (by SIFTS) (P0DTC9) | Severe acute respiratory syndrome coronavirus 2 | |
| 3 | E, F, K, L (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 4 | G, M (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | H, I, J, O (A, B) | BROMIDE ION | non-polymer | 79.9 | 4 | Chemie (BR) | |||
| 6 | N (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 7 | P, Q, R, S (A, B, E, F) | water | water | 18.0 | 338 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 75 | Glu 75 | engineered mutation |
| Ala 76 | Glu 76 | engineered mutation |
| Ala 77 | Lys 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54286.8 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1050.4 | |
| All* | Total formula weight | 55337.2 |
