7QHO

Cytochrome bcc-aa3 supercomplex (respiratory supercomplex III2/IV2) from Corynebacterium glutamicum (as isolated)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, N (A, N)	Cytochrome bc1 complex Rieske iron-sulfur subunit	polymer	408	45232.2	2	UniProt (Q79VE8) Pfam (PF19297) Pfam (PF00355)	Corynebacterium glutamicum ATCC 13032	Cytochrome bc1 reductase complex subunit QcrA,Menaquinol--cytochrome c reductase iron-sulfur subunit,Rieske iron-sulfur protein
2	B, O (B, O)	Cytochrome bc1 complex cytochrome b subunit	polymer	539	59863.7	2	UniProt (Q79VE9) Pfam (PF13631)	Corynebacterium glutamicum ATCC 13032	Cytochrome bc1 reductase complex subunit QcrB,Menaquinol--cytochrome c reductase cytochrome b subunit
3	C, P (C, P)	Cytochrome bc1 complex cytochrome c subunit	polymer	283	29898.8	2	UniProt (Q8NNK5) Pfam (PF00034) Pfam (PF13442)	Corynebacterium glutamicum ATCC 13032	Cytochrome c1,Cytochrome bc1 reductase complex subunit Qcrc,Menaquinol--cytochrome c reductase cytochrome c subunit
4	D, Q (D, Q)	Cytochrome c oxidase subunit 1	polymer	594	66340.2	2	UniProt (Q79VD7) Pfam (PF00115)	Corynebacterium glutamicum ATCC 13032	Cytochrome aa3 subunit 1,Cytochrome c oxidase polypeptide I
5	E, R (E, R)	Cytochrome c oxidase subunit 2	polymer	331	36811.1	2	UniProt (Q8NNK2) Pfam (PF00116)	Corynebacterium glutamicum ATCC 13032	Cytochrome aa3 subunit 2,Cytochrome c oxidase polypeptide II,Oxidase aa(3) subunit 2
6	F, S (F, S)	Cytochrome c oxidase subunit 3	polymer	205	22457.2	2	UniProt (Q9AEL8) Pfam (PF00510)	Corynebacterium glutamicum ATCC 13032	Cytochrome aa3 subunit 3,Cytochrome c oxidase polypeptide III
7	G, T (G, T)	Cytochrome c oxidase polypeptide 4	polymer	143	15557.3	2	UniProt (Q8NNK3) Pfam (PF12270)	Corynebacterium glutamicum ATCC 13032	Cytochrome aa3 subunit 4,Cytochrome c oxidase polypeptide IV
8	H, U (H, U)	Uncharacterized protein Cgl2664/cg2949	polymer	163	16954.2	2	UniProt (Q8NMB4)	Corynebacterium glutamicum ATCC 13032	P29
9	I, V (I, V)	Uncharacterized membrane protein Cgl2017/cg2211	polymer	147	16385.6	2	UniProt (Q8NP09) Pfam (PF10939)	Corynebacterium glutamicum ATCC 13032	P20
10	J, W (J, W)	Hypothetical membrane protein	polymer	112	12144.2	2	UniProt (Q8NTD4)	Corynebacterium glutamicum ATCC 13032
11	K, X (K, X)	Actinobacterial supercomplex, subunit C (AscC)	polymer	73	8373.3	2	UniProt (Q8NS61)	Corynebacterium glutamicum ATCC 13032
12	L, Y (L, Y)	Hypothetical membrane protein	polymer	65	6628.9	2	UniProt (Q8NSJ8)	Corynebacterium glutamicum ATCC 13032
13	M, Z (M, Z)	Thiamine biosynthesis protein X	polymer	168	17152.4	2	UniProt (P42461)	Corynebacterium glutamicum ATCC 13032
14	AA, PB (A, N)	FE2/S2 (INORGANIC) CLUSTER	non-polymer		175.8	2	Chemie (FES)
15	BA, QB (A, N)	[(2~{R})-3-[[(1~{S},2~{R},3~{S},4~{S},5~{R},6~{R})-2-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-[[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-[[(2~{S},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,5-bis(oxidanyl)oxan-2-yl]oxymethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxymethyl]-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,4,5-tris(oxidanyl)-6-[(2~{R},3~{S},4~{S},5~{S},6~{R})-3,4,5-tris(oxidanyl)-6-(undecanoyloxymethyl)oxan-2-yl]oxy-cyclohexyl]oxy-oxidanyl-phosphoryl]oxy-2-undecanoyloxy-propyl] (10~{R})-10-methyldodecanoate	non-polymer		1677.8	2	Chemie (IZL) PubChem (163321808)
16	CA, LA, RB, VC (A, B, N, U)	(2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate	non-polymer		853.1	4	Chemie (9YF) PubChem (134823940)
17	DA, FA, IA, NB, TB... (A, B, N, O)	MENAQUINONE-9	non-polymer		785.2	6	Chemie (MQ9) PubChem (5288844) PubChem (6289935) PubChem (160508) PubChem (163285556)
18	CB, DB, EA, IC, KB... (E, F, A, Q, J...)	1,2-Distearoyl-sn-glycerophosphoethanolamine	non-polymer		748.1	10	Chemie (3PE)
19	GA, HA, UB, VB (B, O)	PROTOPORPHYRIN IX CONTAINING FE	non-polymer		616.5	4	Chemie (HEM)
20	EB, FB, GC, HC, IB... (F, G, Q, I, B...)	CARDIOLIPIN	non-polymer		1464.0	14	Chemie (CDL) PubChem (5287898) PubChem (17753886)
21	KA, YB (B, O)	LYCOPENE	non-polymer		536.9	2	Chemie (LYC) PubChem (3977) PubChem (446925) PubChem (5319123) PubChem (5353730) PubChem (5385555) PubChem (6440310) PubChem (6440363) PubChem (6440364) PubChem (10918539) PubChem (10973519) PubChem (11124358) PubChem (11756979) PubChem (21145326) PubChem (25245411) PubChem (92863368) PubChem (101753434) PubChem (53477748) PubChem (53483360) PubChem (54603520) PubChem (56841918) PubChem (163826994) PubChem (71773487) PubChem (92863365) PubChem (92863366) PubChem (92863367) PubChem (100972459) PubChem (101118616) PubChem (101467043) PubChem (101753435) PubChem (101764620) PubChem (101764621) PubChem (101764622) PubChem (102062446) PubChem (102105948) PubChem (102407971) PubChem (123133982) PubChem (131954643) PubChem (135074778) PubChem (138394743) PubChem (152743366) PubChem (154495923) PubChem (157010101) PubChem (159936649) PubChem (161488819) PubChem (163826995) PubChem (168312947) PubChem (172779219) PubChem (172779220) PubChem (172779221) PubChem (172779222) PubChem (172878403) PubChem (172878665)
22	MA, SB (B, O)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	2	Chemie (LMT)
23	AC, BC, OA, PA (P, C)	HEME C	non-polymer		618.5	4	Chemie (HEC)
24	QA, SC (C, T)	1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE	non-polymer		705.0	2	Chemie (3PH) PubChem (447938) PubChem (16211043) PubChem (86641)
25	CC, DC, RA, SA (Q, D)	HEME-AS	non-polymer		921.0	4	Chemie (HAS)
26	EC, TA (Q, D)	COPPER (II) ION	non-polymer		63.5	2	Chemie (CU) PubChem (27099)
27	FC, UA (Q, D)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA) PubChem (271)
28	JC, YA (R, E)	MANGANESE (II) ION	non-polymer		54.9	2	Chemie (MN) PubChem (27854)
29	AB, KC, LC, ZA (E, R)	DINUCLEAR COPPER ION	non-polymer		127.1	4	Chemie (CUA)
30	BB, GB, LB, MC, TC... (E, H, M, R, U...)	DIACYL GLYCEROL	non-polymer		625.0	6	Chemie (DGA) PubChem (102615) PubChem (9543705) PubChem (11285052)
31	HB, MB, UC, ZC (H, M, U, Z)	PALMITIC ACID	non-polymer		256.4	4	Chemie (PLM)
32	JB, OC (I, R)	[(2~{R})-3-[[(1~{S},2~{R},3~{R},4~{S},5~{S},6~{R})-2-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hexadecanoyloxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-6-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-3,4,5-tris(oxidanyl)cyclohexyl]oxy-oxidanyl-phosphoryl]oxy-2-undecanoyloxy-propyl] (10~{S})-10-methylhenicosanoate	non-polymer		1387.7	2	Chemie (IX7) PubChem (163321807)
33	AD, BD, CD, DD, ED... (B, D, E, O, Q...)	water	water		18.0	10	Chemie (HOH)

Sequence modifications

D, Q: 1 - 584 (UniProt: Q79VD7)

PDB	External Database	Details
Ala 585	-	expression tag
Ala 586	-	expression tag
Trp 587	-	expression tag
Ser 588	-	expression tag
His 589	-	expression tag
Pro 590	-	expression tag
Gln 591	-	expression tag
Phe 592	-	expression tag
Glu 593	-	expression tag
Lys 594	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	26
	Total formula weight	707598.1
Non-Polymers*	Number of molecules	78
	Total formula weight	60313.9
All*	Total formula weight	767912.0

*Water molecules are not included.