7QHJ
Peptide GAKSAA in complex with human cathepsin V C25A mutant
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (AA, BA) | Cathepsin L2 | polymer | 221 | 24021.9 | 2 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (human) | Cathepsin U,Cathepsin V |
| 2 | C, D (PA, PB) | SER-ALA-ALA-AMI | polymer | 8 | 528.6 | 2 | Homo sapiens | ||
| 3 | E, F, G, O, X (AA, BA) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 5 | Chemie (MPD) | |||
| 4 | AA, H, I, L, M... (BA, AA) | GLYCEROL | non-polymer | 92.1 | 12 | Chemie (GOL) | |||
| 5 | J, K, R, S, U (AA, BA) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | T (AA) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 7 | BA, CA, DA, EA (AA, BA, PA, PB) | water | water | 18.0 | 501 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 221 (UniProt: O60911)
| PDB | External Database | Details |
|---|---|---|
| Ala 25 | Cys 138 | engineered mutation |
| Gln 108 | Asn 221 | engineered mutation |
| Gln 179 | Asn 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 49101.1 | |
| Non-Polymers* | Number of molecules | 23 |
| Total formula weight | 1896.3 | |
| All* | Total formula weight | 50997.3 |
