7QFF
Peptide VACKSSQP in complex with human cathepsin V C25A mutant
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (AA, BA) | Cathepsin L2 | polymer | 221 | 24021.9 | 2 | UniProt (O60911) Pfam (PF00112) | Homo sapiens (Human) | Cathepsin U,Cathepsin V |
2 | C, E (PA, PB) | ACE-VAL-ALA-CYS-LYS | polymer | 10 | 844.0 | 2 | unidentified | ||
3 | D (PAB) | GLU-TYR-SER | polymer | 3 | 397.4 | 1 | Homo sapiens | ||
4 | F, G, H, L, N... (AA, BA) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 6 | Chemie (MPD) | |||
5 | I, O (AA, BA) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
6 | J, K, M, Q (AA, BA) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
7 | R (BA) | trifluoroacetic acid | non-polymer | 114.0 | 1 | Chemie (TFA) | |||
8 | S, T, U, V, W (AA, BA, PA, PAB, PB) | water | water | 18.0 | 530 | Chemie (HOH) |
Sequence modifications
AA, BA: 1 - 221 (UniProt: O60911)
PDB | External Database | Details |
---|---|---|
Ala 25 | Cys 138 | engineered mutation |
Gln 108 | Asn 221 | engineered mutation |
Gln 179 | Asn 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 50129.2 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1262.3 | |
All* | Total formula weight | 51391.6 |