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7QFF

Peptide VACKSSQP in complex with human cathepsin V C25A mutant

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(AA, BA)
Cathepsin L2polymer22124021.92UniProt (O60911)
Pfam (PF00112)
Homo sapiens (Human)Cathepsin U,Cathepsin V
2C, E
(PA, PB)
ACE-VAL-ALA-CYS-LYSpolymer10844.02unidentified
3D
(PAB)
GLU-TYR-SERpolymer3397.41Homo sapiens
4F, G, H, L, N...
(AA, BA)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.26Chemie (MPD)
5I, O
(AA, BA)
CHLORIDE IONnon-polymer35.52Chemie (CL)
6J, K, M, Q
(AA, BA)
GLYCEROLnon-polymer92.14Chemie (GOL)
7R
(BA)
trifluoroacetic acidnon-polymer114.01Chemie (TFA)
8S, T, U, V, W
(AA, BA, PA, PAB, PB)
waterwater18.0530Chemie (HOH)
Sequence modifications
AA, BA: 1 - 221 (UniProt: O60911)
PDBExternal DatabaseDetails
Ala 25Cys 138engineered mutation
Gln 108Asn 221engineered mutation
Gln 179Asn 292engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight50129.2
Non-Polymers*Number of molecules13
Total formula weight1262.3
All*Total formula weight51391.6
*Water molecules are not included.

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PDB entries from 2024-11-13

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