7QEN

S.c. Condensin core in DNA- and ATP-bound state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (F)	DNA (35-MER)	polymer	50	15615.4	1		synthetic construct
2	B (G)	DNA (35-MER)	polymer	50	15164.7	1		synthetic construct
3	C (B)	Structural maintenance of chromosomes protein 4	polymer	1478	167716.1	1	UniProt (Q12267) Pfam (PF02463) Pfam (PF06470)	Saccharomyces cerevisiae CEN.PK113-7D
4	D (A)	Structural maintenance of chromosomes protein 2	polymer	1170	134124.9	1	UniProt (P38989) Pfam (PF02463) Pfam (PF06470)	Saccharomyces cerevisiae (baker's yeast)	DA-box protein SMC2
5	E (C)	Condensin complex subunit 2	polymer	811	92721.2	1	UniProt (P38170) Pfam (PF05786)	Saccharomyces cerevisiae (baker's yeast)	Barren homolog,CAPH homolog
6	F (D)	Condensin complex subunit 1	polymer	1176	133116.8	1	UniProt (Q06156) Pfam (PF12922) Pfam (PF12717)	Saccharomyces cerevisiae (baker's yeast)	XCAP-D2 homolog
7	G, I (B, A)	ADENOSINE-5'-TRIPHOSPHATE	non-polymer		507.2	2	Chemie (ATP)
8	H, J (B, A)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)

Sequence modifications

B: 1 - 124 (UniProt: Q12267)

PDB	External Database	Details
Ala 14	Ser 14	conflict
Glu 30	Asp 30	conflict

B: 125 - 140 (PDB: 7QEN)
B: 1 - 1418 (UniProt: Q12267)

PDB	External Database	Details
Ser 143	Arg 143	conflict
Arg 425	Lys 425	conflict
Asp 546	Asn 546	conflict
Ala 697	Val 697	conflict
Ile 704	Val 704	conflict
Asn 1028	Asp 1028	conflict
Thr 1052	Asn 1052	conflict
Asp 1165	Ala 1165	conflict
Val 1177	Ile 1177	conflict
Gln 1352	Glu 1352	engineered mutation
Arg 1419	-	expression tag
Ile 1420	-	expression tag
Pro 1421	-	expression tag
Gly 1422	-	expression tag
Leu 1423	-	expression tag
Ile 1424	-	expression tag
Asn 1425	-	expression tag
Gly 1426	-	expression tag
Ala 1427	-	expression tag
Thr 1428	-	expression tag
Gly 1429	-	expression tag
Trp 1430	-	expression tag
Ser 1431	-	expression tag
His 1432	-	expression tag
Pro 1433	-	expression tag
Gln 1434	-	expression tag
Phe 1435	-	expression tag
Glu 1436	-	expression tag
Lys 1437	-	expression tag
Ala 1438	-	expression tag
Gly 1439	-	expression tag
Gly 1440	-	expression tag
Gly 1441	-	expression tag
Ser 1442	-	expression tag
Gly 1443	-	expression tag
Gly 1444	-	expression tag
Gly 1445	-	expression tag
Ser 1446	-	expression tag
Gly 1447	-	expression tag
Gly 1448	-	expression tag
Gly 1449	-	expression tag
Ser 1450	-	expression tag
Trp 1451	-	expression tag
Ser 1452	-	expression tag
His 1453	-	expression tag
Pro 1454	-	expression tag
Gln 1455	-	expression tag
Phe 1456	-	expression tag
Glu 1457	-	expression tag
Lys 1458	-	expression tag
Gly 1459	-	expression tag
Gly 1460	-	expression tag
Gly 1461	-	expression tag
Ser 1462	-	expression tag
Gly 1463	-	expression tag
Gly 1464	-	expression tag
Gly 1465	-	expression tag
Ser 1466	-	expression tag
Gly 1467	-	expression tag
Gly 1468	-	expression tag
Gly 1469	-	expression tag
Ser 1470	-	expression tag
Trp 1471	-	expression tag
Ser 1472	-	expression tag
His 1473	-	expression tag
Pro 1474	-	expression tag
Gln 1475	-	expression tag
Phe 1476	-	expression tag
Glu 1477	-	expression tag
Lys 1478	-	expression tag

A: 1 - 1170 (UniProt: P38989)

PDB	External Database	Details
Gln 1113	Glu 1113	engineered mutation

C: 1 - 754 (UniProt: P38170)

PDB	External Database	Details
Ala 517	Gly 517	conflict
Leu 755	-	expression tag
Val 756	-	expression tag
Gly 757	-	expression tag
Gly 758	-	expression tag
Gly 759	-	expression tag
His 760	-	expression tag
His 761	-	expression tag
Arg 762	-	expression tag
Pro 763	-	expression tag
His 764	-	expression tag
His 765	-	expression tag
Gly 766	-	expression tag
Gly 767	-	expression tag
His 768	-	expression tag
His 769	-	expression tag
His 770	-	expression tag
His 771	-	expression tag
His 772	-	expression tag
His 773	-	expression tag
Gly 774	-	expression tag
Gly 775	-	expression tag
Arg 776	-	expression tag
Ile 777	-	expression tag
Phe 778	-	expression tag
Tyr 779	-	expression tag
Pro 780	-	expression tag
Tyr 781	-	expression tag
Asp 782	-	expression tag
Val 783	-	expression tag
Pro 784	-	expression tag
Asp 785	-	expression tag
Tyr 786	-	expression tag
Ala 787	-	expression tag
Gly 788	-	expression tag
Tyr 789	-	expression tag
Pro 790	-	expression tag
Tyr 791	-	expression tag
Asp 792	-	expression tag
Val 793	-	expression tag
Pro 794	-	expression tag
Asp 795	-	expression tag
Tyr 796	-	expression tag
Ala 797	-	expression tag
Gly 798	-	expression tag
Ser 799	-	expression tag
Tyr 800	-	expression tag
Pro 801	-	expression tag
Tyr 802	-	expression tag
Asp 803	-	expression tag
Val 804	-	expression tag
Pro 805	-	expression tag
Asn 806	-	expression tag
Tyr 807	-	expression tag
Ala 808	-	expression tag
Ala 809	-	expression tag
Gly 810	-	expression tag
His 811	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	558459.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1063.0
All*	Total formula weight	559522.0

*Water molecules are not included.