7QEI
Structure of human MTHFD2L in complex with TH7299
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 | polymer | 299 | 32390.7 | 1 | UniProt (Q9H903) Pfam (PF00763) Pfam (PF02882) In PDB | Homo sapiens (human) | NADP-dependent methylenetetrahydrofolate dehydrogenase 2-like protein,MTHFD2-like |
| 2 | A | (2S)-2-[[4-[[2,4-bis(azanyl)-6-oxidanylidene-1H-pyrimidin-5-yl]carbamoylamino]phenyl]carbonylamino]pentanedioic acid | non-polymer | 433.4 | 1 | Chemie (9L9) | |||
| 3 | A | 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATR) | |||
| 4 | water | water | 18.0 | 165 | Chemie (HOH) |
Sequence modifications
A: 50 - 347 (UniProt: Q9H903)
| PDB | External Database | Details |
|---|---|---|
| Met 49 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32390.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 940.6 | |
| All* | Total formula weight | 33331.2 |
