7QDO
Cryo-EM structure of human monomeric IgM-Fc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Isoform 2 of Immunoglobulin heavy constant mu | polymer | 440 | 47687.1 | 2 | UniProt (P01871-2) Pfam (PF07654) UniProt (by SIFTS) (P01871) | Homo sapiens (human) | Ig mu chain C region,Ig mu chain C region BOT,Ig mu chain C region GAL,Ig mu chain C region OU |
Sequence modifications
B, A: 228 - 569 (UniProt: P01871-2)
| PDB | External Database | Details |
|---|---|---|
| Met 197 | - | initiating methionine |
| Gly 198 | - | expression tag |
| Ile 199 | - | expression tag |
| Leu 200 | - | expression tag |
| Pro 201 | - | expression tag |
| Ser 202 | - | expression tag |
| Pro 203 | - | expression tag |
| Gly 204 | - | expression tag |
| Met 205 | - | expression tag |
| Pro 206 | - | expression tag |
| Ala 207 | - | expression tag |
| Leu 208 | - | expression tag |
| Leu 209 | - | expression tag |
| Ser 210 | - | expression tag |
| Leu 211 | - | expression tag |
| Val 212 | - | expression tag |
| Ser 213 | - | expression tag |
| Leu 214 | - | expression tag |
| Leu 215 | - | expression tag |
| Ser 216 | - | expression tag |
| Val 217 | - | expression tag |
| Leu 218 | - | expression tag |
| Leu 219 | - | expression tag |
| Met 220 | - | expression tag |
| Gly 221 | - | expression tag |
| Cys 222 | - | expression tag |
| Val 223 | - | expression tag |
| Ala 224 | - | expression tag |
| Glu 225 | - | expression tag |
| Thr 226 | - | expression tag |
| Gly 227 | - | expression tag |
| Ser 314 | Gly 191 | conflict |
| Ser 414 | Cys 291 | conflict |
| Glu 570 | - | expression tag |
| Ile 571 | - | expression tag |
| Ala 572 | - | expression tag |
| Gln 573 | - | expression tag |
| Leu 574 | - | expression tag |
| Glu 575 | - | expression tag |
| Tyr 576 | - | expression tag |
| Glu 577 | - | expression tag |
| Ile 578 | - | expression tag |
| Ser 579 | - | expression tag |
| Gln 580 | - | expression tag |
| Leu 581 | - | expression tag |
| Glu 582 | - | expression tag |
| Gln 583 | - | expression tag |
| Glu 584 | - | expression tag |
| Ile 585 | - | expression tag |
| Gln 586 | - | expression tag |
| Ala 587 | - | expression tag |
| Leu 588 | - | expression tag |
| Glu 589 | - | expression tag |
| Ser 590 | - | expression tag |
| Gly 591 | - | expression tag |
| Gly 592 | - | expression tag |
| Gly 593 | - | expression tag |
| Ser 594 | - | expression tag |
| Gly 595 | - | expression tag |
| Gly 596 | - | expression tag |
| Gly 597 | - | expression tag |
| Ser 598 | - | expression tag |
| Glu 599 | - | expression tag |
| Asn 600 | - | expression tag |
| Leu 601 | - | expression tag |
| Tyr 602 | - | expression tag |
| Phe 603 | - | expression tag |
| Gln 604 | - | expression tag |
| Gly 605 | - | expression tag |
| Gly 606 | - | expression tag |
| Gly 607 | - | expression tag |
| Ser 608 | - | expression tag |
| Trp 609 | - | expression tag |
| Ser 610 | - | expression tag |
| His 611 | - | expression tag |
| Pro 612 | - | expression tag |
| Gln 613 | - | expression tag |
| Phe 614 | - | expression tag |
| Glu 615 | - | expression tag |
| Lys 616 | - | expression tag |
| Gly 617 | - | expression tag |
| Gly 618 | - | expression tag |
| Gly 619 | - | expression tag |
| Ser 620 | - | expression tag |
| Gly 621 | - | expression tag |
| Gly 622 | - | expression tag |
| Gly 623 | - | expression tag |
| Ser 624 | - | expression tag |
| Gly 625 | - | expression tag |
| Gly 626 | - | expression tag |
| Ser 627 | - | expression tag |
| Ala 628 | - | expression tag |
| Trp 629 | - | expression tag |
| Ser 630 | - | expression tag |
| His 631 | - | expression tag |
| Pro 632 | - | expression tag |
| Gln 633 | - | expression tag |
| Phe 634 | - | expression tag |
| Glu 635 | - | expression tag |
| Lys 636 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 95374.1 | |
| All* | Total formula weight | 95374.1 |
