7QCN

Structure of the MUCIN-2 Cterminal domains: vWCN to TIL domains with a C2 symmetry

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Mucin-2	polymer	407	45157.8	2	UniProt (Q02817) Pfam (PF00094) Pfam (PF08742)	Homo sapiens (human)	MUC-2,Intestinal mucin-2
2	C, D (C, D)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
3	E, I (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
4	F, G, H, J, K... (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)

Sequence modifications

A, B: 4360 - 4802 (UniProt: Q02817)

PDB	External Database	Details
-	Phe 4415	deletion
-	Asp 4416	deletion
-	Pro 4417	deletion
-	Pro 4418	deletion
-	Arg 4419	deletion
-	Gln 4420	deletion
-	Glu 4421	deletion
-	Asn 4422	deletion
-	Glu 4423	deletion
-	Val 4564	deletion
-	Asn 4565	deletion
-	Arg 4566	deletion
-	Gln 4567	deletion
-	His 4663	deletion
-	Ser 4664	deletion
-	Ser 4665	deletion
-	Ser 4666	deletion
-	Thr 4667	deletion
-	Thr 4668	deletion
-	Lys 4669	deletion
-	Arg 4670	deletion
-	Pro 4671	deletion
-	Ala 4672	deletion
-	Val 4673	deletion
-	Thr 4674	deletion
-	Val 4675	deletion
-	Pro 4676	deletion
-	Gly 4677	deletion
-	Gly 4678	deletion
-	Gly 4679	deletion
-	Lys 4680	deletion
-	Thr 4681	deletion
-	Thr 4682	deletion
-	Pro 4683	deletion
-	His 4684	deletion
-	Lys 4685	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	90315.6
Branched	Number of molecules	2
	Total formula weight	1821.6
Non-Polymers*	Number of molecules	8
	Total formula weight	1407.4
All*	Total formula weight	93544.7

*Water molecules are not included.