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7QC9

HisF-C9A-D11E-V33A_L50H_I52H mutant in complex with Ni(II) from T. maritima

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Imidazole glycerol phosphate synthase subunit HisFpolymer25327741.71UniProt (Q9X0C6)
Pfam (PF00977)
Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8)IGP synthase cyclase subunit,IGP synthase subunit HisF,ImGP synthase subunit HisF,IGPS subunit HisF
2B
(A)
NICKEL (II) IONnon-polymer58.71Chemie (NI)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D, E, F
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5G
(A)
waterwater18.0193Chemie (HOH)
Sequence modifications
A: 2 - 253 (UniProt: Q9X0C6)
PDBExternal DatabaseDetails
Ser 1-expression tag
Ala 9Cys 9engineered mutation
Glu 11Asp 11engineered mutation
His 50Leu 50engineered mutation
His 52Ile 52engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight27741.7
Non-Polymers*Number of molecules5
Total formula weight341.0
All*Total formula weight28082.7
*Water molecules are not included.

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PDB entries from 2025-12-10

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