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7QBS

B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, S-adenosyl-L-methionine, and peptide bound.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Methyl coenzyme M reductase-arginine methyltransferase Mmp10polymer43647964.91UniProt (A0A832SFM5)
Pfam (PF19238)
UniProt (by SIFTS) (Q8THG6)
Methanosarcina acetivorans
2B
(B)
Peptide from Methyl-coenzyme M reductase subunit alpha from Methanosarcina acetivoranspolymer131499.71UniProt (by SIFTS) (Q8THH1)Methanosarcina acetivorans
3C
(A)
IRON/SULFUR CLUSTERnon-polymer351.61Chemie (SF4)
4D
(A)
FE (III) IONnon-polymer55.81Chemie (FE)
5E
(A)
S-ADENOSYLMETHIONINEnon-polymer398.41Chemie (SAM)
6F
(A)
CO-METHYLCOBALAMINnon-polymer1344.41Chemie (COB)
7G
(A)
SODIUM IONnon-polymer23.01Chemie (NA)
8H, I
(A, B)
waterwater18.0210Chemie (HOH)
Sequence modifications
A: 1 - 411 (UniProt: A0A832SFM5)
PDBExternal DatabaseDetails
Met -24-initiating methionine
Ala -23-expression tag
Ser -22-expression tag
Trp -21-expression tag
Ser -20-expression tag
His -19-expression tag
Pro -18-expression tag
Gln -17-expression tag
Phe -16-expression tag
Glu -15-expression tag
Lys -14-expression tag
Ser -13-expression tag
Gly -12-expression tag
Gly -11-expression tag
Gly -10-expression tag
Gly -9-expression tag
Gly -8-expression tag
Glu -7-expression tag
Asn -6-expression tag
Leu -5-expression tag
Tyr -4-expression tag
Phe -3-expression tag
Gln -2-expression tag
Gly -1-expression tag
His 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight49464.6
Non-Polymers*Number of molecules5
Total formula weight2173.3
All*Total formula weight51637.9
*Water molecules are not included.

226707

PDB entries from 2024-10-30

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